Product Name: 1,5-Diamino-2-methylpentane
Synonyms: Pentane-1,5-diamine, 2-methyl-; 2-Methyl-1,5-pentanediamine
CAS Number: 15520-10-2
Manufacturer: Specialty chemical companies, research supply firms
Recommended Use: Laboratory reagent, chemical synthesis intermediate
Contact Info: Technical service departments, emergency phone numbers listed on product label
Classification: Skin corrosion/irritation, Eye damage/irritation, Acute toxicity (oral, dermal, inhalation), Sensitizer
GHS Label Elements: Corrosive, Harmful
Hazard Statements: Causes severe skin burns and eye damage, harmful if swallowed, may cause an allergic skin reaction, harmful if inhaled
Precautionary Statements: Wear protective gloves and eye/face protection, avoid breathing vapors, wash skin after handling, do not eat, drink or smoke when using this product
Signal Word: Danger
Potential Health Effects: Eye burns, respiratory discomfort, skin blistering, GI distress if ingested, possible sensitization reactions from repeated skin contact
Chemical Name: 1,5-Diamino-2-methylpentane
CAS Number: 15520-10-2
Concentration (%): ≥98% in pure form
Impurities: May contain traces of related diamines, unidentified byproducts (less than 1%)
Molecular Formula: C6H16N2
Molecular Weight: 116.2 g/mol
Inhalation: Remove exposed individual to fresh air. Seek medical attention if breathing becomes difficult, coughing, or symptoms persist. Administer oxygen if breathing distress is significant.
Skin Contact: Immediately flush with large amount of water for at least 15 minutes. Remove contaminated clothing. Seek medical attention for skin burns, blistering, or delayed irritation.
Eye Contact: Rinse eyes with copious amounts of water for at least 15 minutes, lifting eyelids occasionally to ensure irrigation. Medical evaluation is required for any exposure.
Ingestion: Rinse mouth. Do not induce vomiting unless directed by a health professional. Administer water if victim is alert. Immediate medical attention is necessary.
Advice for Medical Responders: Symptomatic treatment, attention to airway, supportive care for tissue damage or allergic reaction.
Suitable Extinguishing Media: Carbon dioxide, dry chemical powder, foam, water spray
Specific Hazards: Emits toxic fumes of nitrogen oxides and carbon monoxide under fire conditions. Vapors can form explosive mixtures with air at elevated temperatures.
Protective Equipment: Self-contained breathing apparatus and protective suit are essential
Firefighting Procedures: Apply water spray to cool containers and absorb heat. Approach fire from upwind to avoid hazardous vapors.
Combustion Products: Ammonia, carbon oxides, nitrogen oxides likely present
Additional Cautions: Avoid direct contact with product and its decomposition vapors. Containers can rupture and fragment when heated intensely.
Personal Precautions: Use chemical splash goggles, gloves, rubber apron, and a respirator if significant vaporization is likely. Evacuate unprotected individuals away from area.
Environmental Precautions: Prevent product from entering soil, sewers, watercourses. Notify authorities in case of significant seepage to environmental systems.
Cleanup Methods: Absorb small spills with inert material like sand or vermiculite. Place in suitable chemical waste containers. Ventilate area. Wipe up remaining material with detergent solution.
Decontamination: Wash spill area with copious water and detergent. Dispose of all cleanup materials as hazardous waste.
Handling: Avoid contact with skin and eyes. Do not breathe vapor or mist. Handle with appropriate personal protective equipment in a well-ventilated chemical fume hood. Dedicated chemical-resistant gloves and splash goggles are strongly advised.
Storage: Store in closed, clearly labeled containers made of compatible materials. Keep container in a tightly sealed, dry, and cool environment away from direct sunlight and sources of ignition.
Incompatible Materials: Strong oxidizers, acids, acid chlorides, anhydrides – avoid close proximity or combined storage.
Specific Precautions: Use dedicated transfer tools. Store separately from food or drink materials. Maintain spill containment and emergency eyewash/shower facilities nearby.
Exposure Limits: Occupational exposure limits not currently established for this compound by OSHA/NIOSH
Engineering Controls: Use chemical fume hood with forced-air ventilation during tasks involving vapor or dust. Minimize aerosol formation.
Personal Protection: Wear chemical-resistant gloves (nitrile or neoprene), impervious apron or lab coat, chemical splash goggles, and, where airborne exposure is likely, a NIOSH-approved respirator suitable for organic vapors and amines.
Hygiene Practices: Wash thoroughly after handling and before eating, drinking, or smoking. Remove contaminated clothing immediately and launder before reuse. Keep PPE and storage areas free of contamination.
Appearance: Clear to slightly yellowish liquid
Odor: Amine-like, pungent
Odor Threshold: Low; readily detectable
pH: Strongly basic in aqueous solution
Melting Point: Approximately -19°C
Boiling Point: 188 – 190°C
Flash Point: 85°C (closed cup, estimate)
Evaporation Rate: Not readily volatile at room temperature
Flammability: Can sustain combustion above flash point
Vapor Pressure: Low at room temperature
Relative Density: About 0.89 – 0.91 g/cm³ at 20°C
Solubility: Miscible in water, soluble in ethanol and most polar solvents
Partition Coefficient (log Kow): Less than 1 (hydrophilic)
Viscosity: Moderate; flows as a liquid at standard conditions
Chemical Stability: Stable at recommended storage conditions; may slowly degrade in presence of air and moisture
Reactivity: Reacts with acids to form salts, releases heat when neutralized
Hazardous Reactions: Violent exothermic reaction with strong oxidizers, possible violent decomposition with halogenated compounds
Decomposition Products: Toxic and irritant gases including nitrogen oxides, ammonia, and carbon oxides
Storage Incompatibilities: Do not store with oxidizers, strong acids, or halogenated organics
Other Notes: Will absorb moisture from air and may emit strong odors if left uncapped
Acute Toxicity: Oral LD50 (rat): 400–700 mg/kg (estimated, limited animal data)
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Short-term Effects: Severe skin and eye irritation or burns, potential respiratory tract irritation or damage, gastrointestinal injury and nausea if swallowed
Long-term Effects: Potential sensitizer causing skin reactions after repeated contact, no known carcinogenicity found in available literature
Symptoms: Redness, blistering, cough, sore throat, nausea, headache, vision changes on contact
Chronic Toxicity: No evidence of systemic toxicity in typical occupational exposure; allergic dermatitis possible on repeated skin contact
Additional Data: No clear evidence for mutagenicity, reproductive, or developmental toxicity based on current studies.
Ecotoxicity: Harmful to aquatic life and microorganisms, especially in concentrated spills
Persistence and Degradability: Biodegradable over time, slower in low-oxygen conditions
Bioaccumulation: Low; compound is hydrophilic and not prone to accumulating in biological organisms
Mobility in Soil: Highly mobile, soluble in water; may contaminate groundwater if spilled in large amounts
Other Hazards: Toxic to aquatic invertebrates at relatively low concentrations, long-term environmental effects possible after chronic release
Disposal Impact: Improper disposal may harm water systems and soils, disrupt local microbial communities.
Disposal Methods: Treat as hazardous chemical waste in accordance with local, state, and federal laws. Do not pour down the drain or allow into surface water or sewer systems. Collect in sealed, labeled containers for specialized chemical disposal.
Recommended Disposal: Incinerate in a licensed chemical incinerator if available, under strictly controlled conditions. Alternately, use a reputable hazardous waste management firm.
Contaminated Packaging: Decontaminate containers before recycling where allowed or treat as hazardous waste for complete disposal.
Additional Precautions: Maintain clear records of waste volume and method; follow site-specific guidance for hazardous organic amines.
UN Number: 2734
UN Proper Shipping Name: Amines, liquid, corrosive, n.o.s. (1,5-Diamino-2-methylpentane)
Transport Hazard Class: 8 (Corrosive substances)
Packing Group: II
Label Requirements: Corrosive (black/white diamond), handle with gloves and goggles
Special Precautions: Secure all containers upright, segregate from foodstuffs, incompatible chemicals, and combustibles during transport. Emergency information and MSDS must accompany cargo.
OSHA Status: Hazardous chemical under the Hazard Communication Standard
TSCA Inventory: Listed or subject to reporting
SARA Title III: Not classified as an extremely hazardous substance; may be subject to release notification under sections 311/312
REACH Status (EU): Substance registration required for import or manufacture above threshold volume
Other International Listings: Included in relevant chemical inventories for Canada, Australia, Japan
Regulatory Notes: Worker training and hazard communication mandatory. Emergency controls for accidental release and spill reporting regulated in most jurisdictions. Site handling plans must comply with local health, safety, and environmental codes.
