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2-Heptanone Material Safety Data Sheet

Identification

Product Name: 2-Heptanone
Chemical Formula: C7H14O
Synonyms: Heptan-2-one, Methyl n-amyl ketone
CAS Number: 110-43-0
Recommended Use: Laboratory chemical, solvent, flavoring agent
Manufacturer: [Name and Address of Manufacturer]
Emergency Phone Number: [Supplier Emergency Contact Number]

Hazard Identification

Classification: Flammable liquid (Category 3); Acute toxicity, oral (Category 4); Eye irritation (Category 2A)
Signal Word: Warning
Hazard Statements: Flammable liquid and vapor; Harmful if swallowed; Causes serious eye irritation
Pictograms: Flame, Exclamation mark
Precautionary Statements: Keep away from heat, sparks, open flames; wash skin thoroughly after handling; avoid breathing vapors; do not eat, drink or smoke during use; wear eye/face protection; in case of fire, use appropriate extinguishing media

Composition / Information on Ingredients

Chemical Identity: 2-Heptanone
Concentration: ≥99%
Impurities/Additives: No significant impurities considered hazardous per 29 CFR 1910.1200

First Aid Measures

Inhalation: Move the person to fresh air; keep at rest in a position comfortable for breathing; seek medical attention if symptoms persist
Skin Contact: Remove contaminated clothing; wash skin thoroughly with soap and water; seek medical advice if irritation develops
Eye Contact: Rinse cautiously with water for several minutes; remove contact lenses if present and easy to do; continue rinsing and seek medical advice
Ingestion: Rinse mouth with water; do not induce vomiting unless advised by medical personnel; seek medical help immediately
Most Important Symptoms: Respiratory and eye irritation, headache, drowsiness or nausea

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, foam, dry chemical, carbon dioxide
Specific Hazards Arising: Releases toxic fumes, such as carbon monoxide and carbon dioxide, under fire conditions
Special Protective Equipment for Firefighters: Self-contained breathing apparatus and full protective clothing; fight fire from a safe distance
Explosion Hazards: Vapors may form explosive mixtures with air; containers may explode in heat of fire

Accidental Release Measures

Personal Precautions: Wear chemical-resistant gloves, goggles, and protective clothing; ensure adequate ventilation
Environmental Precautions: Prevent further leakage or spillage if safe to do so; do not let product enter drains or waterways
Methods for Clean-up: Absorb with inert material (sand, earth); collect and place in closed containers for disposal; clean spill area with water; ventilate the area

Handling and Storage

Safe Handling: Keep container tightly closed; avoid contact with skin, eyes, and clothing; use only in well-ventilated areas; keep away from ignition sources
Hygiene Practices: Wash hands thoroughly after handling; remove and wash contaminated clothing before reuse
Storage Conditions: Store in cool, dry, well-ventilated place; keep away from direct sunlight, heat, and incompatible materials such as strong oxidizers

Exposure Controls and Personal Protection

Occupational Exposure Limits: ACGIH TLV: 50 ppm TWA (skin); OSHA PEL: 100 ppm TWA
Engineering Controls: Use local exhaust or general dilution ventilation to minimize exposure
Personal Protective Equipment: Chemical splash goggles, chemical-resistant gloves, lab coat or apron, vapor respirator when ventilation is inadequate
Environmental Controls: Use containment to avoid environmental release

Physical and Chemical Properties

Appearance: Colorless liquid
Odor: Fruity, banana-like
Boiling Point: 151°C (304°F)
Melting Point: -35°C (-31°F)
Flash Point: 41°C (106°F) closed cup
Auto-Ignition Temperature: 415°C (779°F)
Vapor Pressure: 3.2 mmHg at 25°C
Density: 0.82 g/cm³ at 20°C
Solubility: Slightly soluble in water, miscible with alcohol and ether
Evaporation Rate: 0.11 (n-butyl acetate=1)
Partition Coefficient (log Kow): 1.98

Stability and Reactivity

Chemical Stability: Stable under normal conditions of use and storage
Reactivity: No dangerous reactions known under recommended conditions
Incompatible Materials: Strong oxidizers, strong acids
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, other toxic fumes
Conditions to Avoid: Excess heat, open flames, sparks, incompatible materials

Toxicological Information

Acute Toxicity: Oral LD50 (rat) 1600 mg/kg; Dermal LD50 (rabbit) >2000 mg/kg
Inhalation: May cause irritation to respiratory tract; high concentrations cause dizziness, headaches
Skin Contact: Slight irritant
Eye Contact: Moderate irritant
Chronic Effects: May cause central nervous system effects, no studies indicating carcinogenicity to date
Note: Not listed by NTP, IARC, or OSHA as a carcinogen

Ecological Information

Ecotoxicity: Low to moderate toxicity to aquatic life
Persistence and Degradability: Readily biodegradable in the environment
Bioaccumulative Potential: Low
Mobility in Soil: Expected to have moderate mobility
Other Adverse Effects: No data indicating significant adverse effects on the environment

Disposal Considerations

Waste Disposal Method: Dispose of in accordance with federal, state, and local environmental regulations; incineration in a chemical incinerator equipped with an afterburner and scrubber is preferred
Contaminated Packaging: Empty containers should be disposed of as hazardous waste; do not reuse packaging
Special Precautions: Prevent spillage from reaching soil, waterways, or drains during disposal

Transport Information

UN Number: UN 1110
UN Proper Shipping Name: Heptanones
Transport Hazard Class: 3 (Flammable liquids)
Packing Group: III
Environmental Hazards: Not classified as a marine pollutant
Special Precautions for Transport: Ensure containers remain upright and secure during transit; follow local transport regulations

Regulatory Information

OSHA: Classified hazardous per OSHA Hazard Communication Standard
TSCA: Listed
SARA Title III: Not subject to Section 313 reporting requirements
California Proposition 65: Not listed
WHMIS Classification (Canada): Class B2 (Flammable Liquid), D2B (Toxic Material Causing Other Toxic Effects)
Other Regulations: Follow all applicable national and regional local regulations regarding chemical safety and environmental protection