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Alpha-Amyl Cinnamaldehyde: Looking Past the Basics

Historical Development

Alpha-Amyl Cinnamaldehyde (ACA) traces its roots to a bigger story about how the fragrance and flavor industries hunt for new scents and tastes. Centuries ago, people relied on crude plant extracts, but the late nineteenth and early twentieth centuries brought breakthroughs in organic synthesis. Chemists figured out how to mimic and modify molecules from the cinnamon tree, seeking robust aroma chemicals for soaps, perfumes, and food. ACA emerged from this curiosity-driven work. Over time, manufacturing shifted from plant extraction to controlled lab synthesis. Companies in Europe and Asia built on early patents, turning an exotic spice component into a staple molecule. Since then, ACA’s production has grown alongside expanding consumer demand for consistent, warm flavor notes and lasting scents. This history isn’t just about chemistry. It reminds us whole industries reshape themselves for higher yields, price stability, and reliable sourcing. Reliability becomes critical when a fragrance goes global, showing up in every corner shop—and ACA helped bridge that move from niche extract to worldwide staple.

Product Overview

ACA gets sold to perfumers and food producers as a clear to slightly yellow liquid, famous for its sweet and spicy aroma. It lands in hundreds of everyday products—chewing gum, soft drinks, air fresheners, detergents. The reason is simple: ACA holds onto its spicy warmth in harsh conditions like high heat in factories or mixing vats with rough chemicals. Its steady scent profile doesn’t shift much from batch to batch, either. All this reliability in smell and taste lets companies standardize their brands, knowing the cinnamon character will always land right. From years in the lab, people appreciate ACA’s flexible presence. You notice it in a bakery aisle or a fresh load of laundry and probably didn’t realize you had a chemist on the job, making sure that comfort stays the same every time.

Physical & Chemical Properties

Industry handbooks file ACA under CAS number 101-39-3. The molecule is built on a cinnamaldehyde backbone, with an extra amyl side-chain attached at the alpha position. ACA holds a melting point well below room temperature, so it stays liquid. Its boiling point hovers around 320°C, high enough to keep it intact in regular processing but not so high you can’t distill it. Water barely touches ACA because of its nonpolar structure, but it mixes well with alcohols, oils, and solvents. Its density comes in just a notch beneath water. ACA brings a refractive index that perfumers use as a fingerprint—helpful when they want to make sure they haven’t been sold a knockoff. This physical stability has its perks: storage tanks don’t corrode, labels don’t fade, and workers spend less time handling surprises.

Technical Specifications & Labeling

Run a technical datasheet for ACA and you’ll find purity reported in percentages, usually 97% or higher. Impurities—side-products, leftover solvents—get flagged fast, because regulatory authorities step in if food contact is possible. Labels list lot numbers, expiration dates, recommended handling temperatures, and hazard symbols for skin and eye irritation. Packing goes into steel drums, HDPE containers, or glass if dealing with small supplies for a research lab. Labels also note compliance markers for REACH in Europe, TSCA in the States, or the Japan Chemical Substances Control Law. These regulations don’t come as a formality. Anybody who’s dealt with a recall from mislabeling knows just how much money and reputation are on the line. Traceability protects both the producer and the consumer, ensuring that everything matches up if the authorities pay a visit.

Preparation Method

ACA typically gets built by chemical condensation of benzaldehyde with an aliphatic aldehyde or alcohol, relying on acid or base catalysts to speed the process. After that, the product mixture passes through distillation columns to strip off unreacted starting materials, water, and side-products. The specific temperatures and pressures get fine-tuned with years of plant floor experience, because waste and yield directly affect the bottom line. The finished product rests in holding tanks until it meets purity checks. Labs might use gas chromatography and mass spectroscopy to double-check the chemical fingerprint. Process engineers always look for ways to lower energy use during distillation or swap in greener catalysts, prompted by rising fuel costs and tighter emissions standards. Practical ideas—good insulation, heat-exchanger upgrades—cut bills and help reduce the plant’s footprint.

Chemical Reactions & Modifications

Once in the bottle, ACA acts as a versatile starting point for building even more complex aroma compounds. Chemists use it as a scaffold, adding or swapping groups to tune scent or taste: turning that amyl side-chain into something bulkier, or slipping in oxygen or nitrogen atoms for new effects. Oxidation and reduction reactions can tweak the flavor toward more floral or even spicy pepper notes. These types of modifications keep research labs humming, as companies constantly chase new market trends—whether the world wants its cinnamon ‘cleaner,’ warmer, or bolder. Synthetics let them leap past the limitations of seasonal crops, drought, or plant disease. Still, every new molecule demands fresh safety checks, so there’s always a real cost in chasing novelty for novelty’s sake.

Synonyms & Product Names

Chemists, suppliers, and product developers know ACA under several names: 2-benzylideneheptanal, alpha-amyl cinnamic aldehyde, or even just amyl cinnamal in regulatory documents. At fragrance trade shows, the same molecule picks up fancy brand names, tailored for marketing. The core idea stays the same because buyers need consistency and cross-checking a shipment’s identity is easier when everybody speaks the same chemical language. Import documents, technical sheets, and customs entries use these synonyms to prevent confusion during global trade. Fancy naming can sometimes cloud what you’re really using, making it crucial for technical folks to keep their glossaries up to date.

Safety & Operational Standards

No matter how useful ACA proves, its safety profile cannot get ignored. Direct skin contact can cause sensitization—meaning some users break out in rashes or hives, especially workers who handle bulk shipments day in and day out. Eye contact leads to stinging and redness, swallowing concentrated ACA can hurt the gastrointestinal tract. Labels from chemical suppliers direct users toward gloves, splash goggles, and proper ventilation. Fire remains a minor risk thanks to a flash point well above room temperature, yet spills on a hot surface will ignite. Regulations direct companies to keep ACA tanks away from oxidizers and open flames and to equip storage areas with spill kits and emergency showers. In reality, accidents on the plant floor rarely happen when people follow the rules. Most injuries result from shortcuts or ignored warning labels, so regular safety audits and proper training make a practical difference.

Application Area

You run into ACA across a surprising range of products. In perfumery, it acts as a top and middle note, blending into everything from clean colognes to spicy orientals. Flavor houses use it for bakery items, cinnamon gum, and holiday-themed candies. Its stability in detergent and air-freshener formulas lets household product companies trust their scents won’t fade during transport or months of storage. Even in the plastics and coatings world, ACA finds a spot, masking chemical odors in vinyl or shoe soles. Each field values ACA for slightly different reasons—perfumers for subtlety, food producers for taste, consumer goods manufacturers for scent retention under harsh processing or long shelf-life. Over the years I’ve watched even conservative brands switch to ACA to keep costs predictable against swings in natural cinnamon supply.

Research & Development

Research labs look at ACA as a launching point for new scent molecules. Academic teams tinker with the side-chains, pushing for more nuanced or niche aroma profiles. Big flavor firms screen hundreds of ACA derivatives each year, searching for the next must-have note in beverages or ice cream. Green chemistry prompts drive development of new processes with less waste, or which swap toxic reagents for ones that break down safely. Digital modeling and artificial intelligence now help chemists predict how new analogs will perform, saving money and time compared to pure trial-and-error. Universities sometimes work with government grants, tracking how metabolites of ACA break down in the environment, or pass through the food chain from flavorings into the human body. Industry and academia both realize the balance—innovation keeps customers interested, but new products must stay safe, legal, and environmentally responsible.

Toxicity Research

Scientists have spent decades studying ACA’s toxicity, especially due to its use in food and cosmetic products. Animal studies show that the molecule gets metabolized quickly, not building up in fat or organs. High doses spark mild irritation, but much bigger issues pop up with people who become sensitized over time. European and US regulators keep reviewing new safety data, sometimes restricting maximum permitted levels in consumer products, especially children’s toys and skincare items. Epidemiologists track workplace exposure incidents, helping employers set guidelines for ventilation and daily limits. Consumer safety groups push companies to publicize all test results and phase out older formulas if safer alternatives appear. Over the years, ACA has earned a reputation for relative safety, but as anyone who’s seen an allergic reaction firsthand can attest—rare side effects become headline news when products reach millions. Vigilance and transparency set good companies apart.

Future Prospects

Looking forward, ACA stands at a crossroads familiar to many synthetic aroma chemicals. Consumers and brands question both the health and environmental impact of every additive, even ones considered safe for decades. R&D keeps improving green synthesis, using renewable feedstocks or fully bio-based routes to lessen reliance on fossil fuels. Brands aiming for “natural” labels hunt for ACA analogs derived from fermentation or engineered yeasts, hoping to match the performance of synthetic versions. Regulators may tighten limits if new toxicity or environmental data emerge, pushing industry to adapt quickly. AI-driven aroma design could open up whole new families of ACA-related chemicals within just a few years, changing the landscape for perfumers and flavorists alike. As someone who’s watched these cycles play out, I know that adaptability, science-backed transparency, and honest risk assessment will matter more with every passing year—making ACA a useful case study for the modern chemical industry.



What is Alpha-Amyl Cinnamaldehyde (ACA) used for?

The Scent Behind Countless Products

Open a bottle of high-end perfume or a well-formulated lotion and a warm, spicy-sweet aroma usually wafts up. That signature scent often ties back to alpha-amyl cinnamaldehyde (ACA). As someone who grew up around a family-run bakery, the sweet, slightly fruity smell always lit up the kitchen after busy mornings. Later, I found out chemists have bottled versions of that sensation, crafting it with molecules like ACA for a reliable, pleasant twist.

In fragrances and fine cosmetics, ACA gives products a natural, cinnamon-like depth. Sometimes perfumers call it “nature-identical” because it mimics the essential oils people know and love. Packaging professionals and formulators turn to ACA to mask less-pleasant base odors in soaps, shower gels, and detergents. It’s a staple in the toolkit of anyone trying to elevate the possibility for instant comfort—one sniff and you’re transported to cozier days.

Food and Drink: A Hint of the Familiar

Flavor chemists understand memory works right through the nose and tongue. ACA has appeared in the food industry for decades, especially in sweets and chewing gum. That touch of spicy warmth helps candy taste a little fresher, baked goods echo old-fashioned recipes, and beverages grab attention. Regulatory agencies, like the Food and Drug Administration and the Joint FAO/WHO Expert Committee on Food Additives, have approved limited amounts for food use. Their stamp matters to scientists and health professionals who want clean, consistent labeling and safe products for every shelf.

Eating, smelling, and feeling familiar comforts has a different meaning for families who are cautious about chemical additives. Transparency in ingredient sourcing stood out as an issue. Manufacturers do keep an eye on research about allergic reactions or sensitivities; I’ve met parents checking ingredient lists and calling support lines just to make sure a treat’s safe. The reality is, ACA’s use remains low-level, adding layers of scent and flavor without overtaking the recipe. Still, industry watchers should keep track of evolving regulations and new food safety studies.

Household and Health: Everyday Touches

Cleaning sprays, air fresheners, and shampoos often feature ACA, hidden beneath trade names on labels. If a room freshener boasts a cozy, spicy scent, or laundry powder promises lingering warmth, chances are ACA played a part. These products, simple as they seem, make a big difference for people looking for that “just-cleaned” feeling, or parents hoping to mask the smell of sports gear after a weekend game.

Some health professionals worry about overexposure to synthetic fragrances, especially for folks dealing with asthma or skin sensitivities. These issues raise questions about how much ACA we can handle safely. As consumer interest in natural and hypoallergenic choices rises, companies need to test alternative blends and share clear information. Investing in third-party testing and transparency opens trust between brands and those reading the fine print at the store.

Balancing Art, Science, and Safety

ACA stands at the crossroads of creativity and safety. Chemists and flavorists create experiences that stick with us, building trust in familiar scents and tastes. At the same time, real scrutiny over safety ensures companies respect the health of the people buying their products. Consumer watchdogs and advocacy groups keep up the pressure for science-backed decision making and honest ingredient disclosure.

From perfumes to pastries, alpha-amyl cinnamaldehyde makes daily life a bit more inviting. Paying attention to evolving research, regulatory shifts, and real-world feedback from users helps everyone—from the chemists behind the scenes to families in kitchens and bathrooms—enjoy the right balance of comfort and confidence.

Is Alpha-Amyl Cinnamaldehyde safe for use in cosmetics and fragrances?

What is Alpha-Amyl Cinnamaldehyde?

Walk into a perfumery or pick up a moisturizer at the store and chances are high you’ll see a long, science-like ingredient list. One name that pops up often in both perfumes and beauty products is Alpha-Amyl Cinnamaldehyde. This compound brings a sweet, floral, cinnamon-like scent, which explains its popularity with fragrance makers and cosmetic chemists. You might find it listed on ingredient labels as part of the blend that gives creams and lotions their signature aroma.

Science Behind the Smell

Strictly speaking, this ingredient is derived from cinnamon bark and certain plants, but most often, companies produce it synthetically. Fragrance companies have relied on it for years to add warmth and depth to scent mixes. Its distinct profile means it has a fan base far beyond just the perfume counters—soaps, shampoos, and air fresheners pick it up too.

Are There Safety Concerns?

Here’s where things get interesting for anyone who pays attention to what goes on their skin. Regulatory bodies in the US and Europe recognize Alpha-Amyl Cinnamaldehyde as safe for use in cosmetics, but only up to certain concentrations. The European Union, in particular, keeps a sharp eye on this chemical. The International Fragrance Association (IFRA) has set specific usage limits, especially in products left on the skin. Studies have linked some natural and synthetic fragrance ingredients to skin sensitization, which basically means allergies can show up in people sensitive to fragrances after repeated exposure.

Research shows only a small percentage of people develop reactions to Alpha-Amyl Cinnamaldehyde. Patch testing in dermatology clinics finds that most folks tolerate it just fine, but a small number of users report redness, itching, or swelling after using a product that contains it. The risk seems higher in people with sensitive or broken skin, or among those who already deal with eczema or allergies.

Regulation, Labeling, and Real-World Choices

Labeling laws in places like Europe help consumers spot potential irritants. Manufacturers must clearly list Alpha-Amyl Cinnamaldehyde if it reaches a certain threshold in a product’s formula. This transparency allows people with fragrance allergies or skin issues to avoid problematic ingredients. The US lags behind on this front. Lawmakers have looked at updates to labeling rules, but at the moment, companies often group fragrance ingredients under catch-all terms like “parfum” or “fragrance,” so shoppers don’t always know exactly what they’re putting on their skin.

Personal Experience and Practical Advice

As someone who’s wrestled with sensitive skin throughout my life, decisions about products on my bathroom shelf matter. I track down ingredient lists, check for reported allergens, and patch test whenever I try something new. The science shows Alpha-Amyl Cinnamaldehyde causes real issues only for a minority of users, but a patch test before slathering a new cream or spritzing a new perfume saves a lot of discomfort.

Brands have started formulating fragrance-free or hypoallergenic options knowing that people want that choice. Dermatologists suggest opting for these, especially if you’ve had past reactions or deal with chronic skin conditions.

Moving Toward Solutions

The industry needs to keep researching ingredient safety—especially for people with sensitive skin and for long-term effects. Tougher labeling laws would help everyone make better choices, not just those who know how to read a technical ingredient list. Brands can do more to educate shoppers and offer fragrance-free alternatives. At home, reading up, patch testing, and speaking regularly with a dermatologist give anyone the tools to find out what works best for their own skin.

What are the physical and chemical properties of Alpha-Amyl Cinnamaldehyde?

Getting Acquainted With a Unique Aroma Compound

Step into a world of flavor and fragrance, and you'll probably find alpha-amyl cinnamaldehyde working behind the scenes. Known best for its warm, spicy scent with fruity undertones, this compound serves as a classic example of how chemistry shapes sensory experiences. Science pegs it as a pale yellow liquid, standing out with a characteristic sweet-spicy aroma that perfumers and flavorists chase. It hardly dissolves in water but loves mixing with alcohol and oils. This trait eases its way into perfumes, baked treats, and even some personal care products.

Physical Properties

Alpha-amyl cinnamaldehyde pours as a clear liquid, ranging from colorless to a subtle straw shade. Its melting point lingers below room temperature, which keeps it liquid in most storage situations. A boiling point around 305°C gives it decent stability during production and transport. Not everything is sunshine, though—this molecule can irritate skin upon contact, which keeps safety goggles and gloves in fashion at labs and factories.

The real twist? Its density runs higher than water, and it drifts through the air with a very low volatility compared to lighter aldehydes. Imagine a perfume that lingers softly on the skin; that fixative quality lets complex base notes last longer. Scents in soaps, lotions, and even air fresheners lean on this behavior. Storage brings its own quirks, since it's light-sensitive and slowly oxidizes in open air. Anyone who’s lost a favorite bottle of fragrance to age knows how exposure to sunlight and air shortens shelf life.

Chemical Characteristics

The backbone of alpha-amyl cinnamaldehyde holds a phenyl ring joined to a highly reactive aldehyde group and a branched amyl chain. The molecule reacts easily with oxygen, acids, and bases—a trait with upsides and downsides.

Routine chemical changes drive the formation of derivatives for specialty applications. Mix it with hydrogen peroxide and you might get more stable forms, opening pathways to new flavors or pharmaceutical intermediates. In the wrong hands, these reactions can also create unwanted byproducts, including possible allergens. The European Chemicals Agency notes sensitization concerns, especially in people prone to contact dermatitis. Brands are taking note; regulations tighten around exposure levels in consumer products, echoing shifts in how companies handle other flavor and fragrance chemicals like coumarin or eugenol.

Risks and Strategies for Safer Use

No one likes surprises in the lab or on the skin. Low water solubility makes clean-up tough and spillage a problem for waterways. Inhaling high concentrations brings on coughing fits and headaches, common for many aldehydes. Safety goggles, gloves, and solid ventilation in work areas shield crews from harm. On a commercial scale, using closed systems and carbon filters minimizes exposure risks during mixing, bottling, and transport.

Safer formulations depend on partnerships between manufacturers, regulators, and researchers. Regular review of new toxicology findings means updates to allowable concentrations happen before issues go public. Investing in greener chemistry, like developing less reactive analogues, promises the next big leap in both safety and versatility. The more the industry listens to toxicologists and frontline workers, the better we’ll get at harmonizing the best in scent with the safest practices available.

Looking Ahead

Alpha-amyl cinnamaldehyde delivers a punchy, long-lasting aroma but asks for respect in how it’s managed and used. Keeping workers protected, monitoring environmental release, and constantly reviewing scientific advances—these steps set the stage for a future where delightful smells and safe products go hand-in-hand.

Does Alpha-Amyl Cinnamaldehyde have any known allergens or side effects?

Everyday Products and Rising Curiosity

Alpha-amyl cinnamaldehyde shows up in so many personal products I’ve used over the years. Colognes, body washes, scented candles—sometimes it sits on a label under names most people overlook. The sweet, spicy aroma draws companies to it, especially since it comes close to that familiar, comforting cinnamon scent. Long before I started watching my allergies closely, I never thought twice about these ingredients. Then I heard from friends who started sneezing, coughing, or getting rashes out of nowhere after using a new perfume or cleaning spray. That’s when I began to pay more attention.

Potential for Reactions

For a lot of folks, alpha-amyl cinnamaldehyde passes by unnoticed and seems harmless. Sensitive skin or a family history of allergies can tilt the odds. Dermatologists and allergists say this compound counts as an established skin sensitizer. Patch tests from clinics in Europe put it on lists with other fragrances flagged for triggering eczema or contact dermatitis. In my own circle, those with known perfume allergies told me this specific ingredient can set off red, itchy patches. The European Union tracks it closely under cosmetics rules. They demand a label warning if concentrations reach certain levels in a finished product.

What Science Tells Us

Peer-reviewed journals have documented allergic contact dermatitis due to alpha-amyl cinnamaldehyde. Numbers don’t stack up to allergens like nickel or poison ivy, but cases keep popping up among frequent fragrance users. It’s also important to know about respiratory symptoms. High exposures, especially in workplaces where fragrances get manufactured or mixed, can lead to asthma-like reactions. The International Fragrance Association recognizes these issues. So do chemists who work in occupational health, who often mention it during safety briefings for workers handling raw fragrance compounds.

Solutions—Real Steps, Not Just Advice

Instead of living in fear of another itchy rash, try a few practical steps. Reading product labels makes a difference if you know about fragrance allergies. I used to grab whatever laundry detergent smelled best. Now, I double-check ingredients, or stick to fragrance-free formulas during flare-ups. Dermatologists recommend patch testing for anyone with recurring redness or swelling after using perfumed products. One appointment could save a ton of frustration.

Manufacturers can help, too. Corporations know more people read ingredients these days. Some have started listing detailed fragrance information on packaging or company websites. It’s worth reaching out to customer support—many have ingredient lists ready for folks with allergies. Healthcare pros push for clearer labeling, especially in global markets, so that someday everyone will know what’s hiding in that “fragrance” umbrella.

On the legislative front, updates keep rolling out in the European Union and United States. Regulators keep a running tally of ingredients that cause trouble for a chunk of the population. Perhaps over time, national agencies will raise awareness and keep pushing companies to list common allergens precisely, not just under vague names. Until then, people share tips and keep swapping stories about what works—or what leads to an angry patch of skin.

Staying Safe for Sensitive Users

Learning about specific potential allergens like alpha-amyl cinnamaldehyde felt like opening a window. By knowing the name, not just smelling the scent, you can steer clear of surprises. That’s become more important as fragrances sneak into an ever-wider circle of products. If you’ve struggled with reactions to scent, your doctor or dermatologist stands as your best ally. Mutual trust between users, industry, health professionals, and policy makers will clear a path to safer routines for all of us.

In what concentrations is Alpha-Amyl Cinnamaldehyde typically applied in products?

Why Folks Care About Alpha-Amyl Cinnamaldehyde

Step inside a bakery, and the first impression often comes from the warm, sweet aroma. That scent rarely happens by chance. Perfume noses and formulators turn to compounds such as Alpha-Amyl Cinnamaldehyde to build those inviting notes—whether it lands in a high-end perfume, a humble hand soap, or a snack fresh from the supermarket shelves. There's an art to using it, but science sets the boundaries. The big question on my mind: How much can go in before safety, and not just scent, becomes the story?

Regular Use and Setting the Limits

In most perfumery, Alpha-Amyl Cinnamaldehyde holds strong at extremely low levels—think well below 0.1% in finished products. The International Fragrance Association (IFRA) keeps tight tabs: leave-it-on products like lotions rarely reach above 0.05%. Rinse-off items, like shower gels or hand washes, see limits stretching up towards 0.1%, but not much higher. If we talk about fine fragrances, limits sometimes reach 0.1% to 0.2%, guided by skin sensitization studies and decades of patch testing.

Food gets trickier to pin down. The Joint FAO/WHO Expert Committee on Food Additives calls Alpha-Amyl Cinnamaldehyde safe in such minuscule amounts that, if you measured by household kitchen spoons, you'd need a microscope. Maximum approvals in foods might sit from 1 part per million (ppm) up to about 10 ppm, usually only in baked goods, candies or beverages where it works together with other flavors.

Staying Safe Without Giving Up Flavor or Fragrance

Why these caps? Stories from dermatologists remind us: even compounds with lovely scents can irritate skin when added in reckless doses. I once saw a batch of craft soap go awry in a community workshop—just one miscalculation left folks with itchy patches. Skin sensitization sits at the center of regulator concern, so scientists run plenty of tests to clarify what the average body will tolerate. The European Union’s Cosmetics Regulation lists Alpha-Amyl Cinnamaldehyde as an allergen that manufacturers must declare if it pops up above 0.001% in leave-on products or 0.01% in rinse-offs.

If a fragrance formulator wants to push boundaries, testing and documentation must back every move. Most reach for more rounded scent blends instead of just cranking up a single aroma chemical. Safety always makes for a better story than a bold new scent with side effects.

Smart Choices for Manufacturers and Consumers

Big brands and artisan producers share similar goals: deliver a sense of delight, but not at the expense of well-being. Factories and indie makers double-check suggested use levels from suppliers and dive into IFRA guidelines before batching new products. Investment in better testing makes it harder for rogue players to cut corners.

Shoppers have more power now to ask questions about what’s in their products. Labels provide clearer information, especially in spots governed by European cosmetic law or strict American disclosure. Allergy-prone customers look for signals, and the rise of clean beauty rewards companies transparent about what goes in each bottle.

Balancing allure with caution forms the backbone of using Alpha-Amyl Cinnamaldehyde well. Smart formulation builds trust. Following regulations does more than check a box—it keeps that delightful first whiff something everyone can enjoy, free of surprise reactions.

Alpha-Amyl Cinnamaldehyde (ACA)
Names
Preferred IUPAC name (E)-3-phenyl-2-propenal
Other names 2-Propenal, 3-phenyl-, (2E)-
Cinnamaldehyde
Cinnamal
trans-Cinnamaldehyde
Cinnamic aldehyde
Cinnamyl aldehyde
3-Phenyl-2-propenal
Pronunciation /ˈæl.fə ˈæmɪl sɪˈnæm.əlˌældaɪd/
Identifiers
CAS Number 122-40-7
Beilstein Reference 2038752
ChEBI CHEBI:34638
ChEMBL CHEMBL44358
ChemSpider 126020
DrugBank DB14070
ECHA InfoCard 03f413978dae-48e9-b80a-0ed81ae5f4c0
EC Number 4.1.2.41
Gmelin Reference 7928
KEGG C16614
MeSH D000602
PubChem CID 5362439
RTECS number DJ8925000
UNII 47016-77-3
UN number UN3334
Properties
Chemical formula C12H16O
Molar mass 204.31 g/mol
Appearance Light yellow liquid
Odor sweet floral jasmine oily
Density 0.994 g/cm³
Solubility in water Insoluble
log P 3.7
Vapor pressure 0.000361 mmHg at 25°C
Acidity (pKa) 12.73
Basicity (pKb) 8.37
Magnetic susceptibility (χ) -72.6e-6 cm³/mol
Refractive index (nD) 1.5900
Viscosity 24 mPa.s
Dipole moment 3.45 D
Thermochemistry
Std molar entropy (S⦵298) 489.60 J·mol⁻¹·K⁻¹
Std enthalpy of formation (ΔfH⦵298) -139.5 kJ/mol
Std enthalpy of combustion (ΔcH⦵298) -5092 kJ/mol
Pharmacology
ATC code A01AA24
Hazards
Main hazards Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause an allergic skin reaction. Toxic to aquatic life with long lasting effects.
GHS labelling GHS07, GHS09
Pictograms GHS02, GHS05, GHS07
Signal word Warning
Hazard statements H317: May cause an allergic skin reaction. H411: Toxic to aquatic life with long lasting effects.
Precautionary statements P264, P273, P280, P302+P352, P305+P351+P338, P333+P313, P337+P313, P362+P364
NFPA 704 (fire diamond) 2-2-2
Flash point 94 °C
Autoignition temperature 220 °C
Lethal dose or concentration LD₅₀ (oral, rat): 3,100 mg/kg
LD50 (median dose) LD50 (rat, oral): 3,100 mg/kg
PEL (Permissible) PEL: Not established
REL (Recommended) REL (Recommended Exposure Limit) of Alpha-Amyl Cinnamaldehyde (ACA) is "0.05 mg/m³".
IDLH (Immediate danger) Not established
Related compounds
Related compounds Cinnamaldehyde
Benzaldehyde
Cinnamic alcohol
Cinnamic acid
Phenylacetaldehyde