Product Name: Diisobutylamine
Chemical Name: N,N-Diisobutylamine
CAS Number: 110-96-3
Synonyms: 2-Methyl-1-propanamine, N-iso-Butyl-2-methyl-2-propanamine
Recommended Use: Intermediate in organic synthesis, catalyst, corrosion inhibitor
Supplier: Refer to manufacturer or distributor on packaging
Emergency Phone Number: Available on shipping documents and manufacturer’s MSDS
Classification: Flammable liquid (Category 3), Acute Toxicity Oral (Category 4), Skin Corrosion/Irritation (Category 2), Eye Damage/Irritation (Category 2A), Acute Toxicity Inhalation (Category 4)
Label Elements: Signal word: Danger. Highly flammable liquid and vapor. Harmful if swallowed, inhaled, or in contact with skin. Causes skin and eye irritation.
Hazard Statements: H226: Flammable liquid and vapor. H302: Harmful if swallowed. H315: Causes skin irritation. H319: Causes serious eye irritation. H332: Harmful if inhaled.
Precautionary Statements: Keep away from heat, sparks, open flames. Do not eat, drink or smoke during use. Use protective equipment. Avoid breathing vapors or spray mist.
Routes of Exposure: Inhalation, ingestion, skin and eye contact.
Target Organs: Respiratory system, skin, eyes.
Chemical Identity: Diisobutylamine
CAS Number: 110-96-3
EC Number: 203-819-5
Concentration: >99% by weight
Impurities: Minor residuals, not typically hazardous under normal conditions of use.
Stabilizers/Additives: None required to maintain product integrity.
Inhalation: Move person to fresh air immediately. If breathing becomes difficult, seek medical attention as soon as possible. Monitor for respiratory distress.
Skin Contact: Remove contaminated clothing. Wash skin with plenty of water and soap for at least 15 minutes. Consult physician if irritation persists.
Eye Contact: Rinse cautiously with water for at least 15 minutes. Lift eyelids occasionally. Remove contact lenses if present and easy to do. Seek medical help promptly.
Ingestion: Rinse mouth thoroughly with water. Do not induce vomiting. Keep person calm and get immediate medical attention.
Most Important Symptoms: Causes irritation; headache, dizziness possible if inhaled; severe eye irritation, possible burns; dermatitis on repeated skin exposure.
Suitable Extinguishing Media: Alcohol-resistant foam, dry chemical, carbon dioxide. Do not use water jets directly.
Specific Hazards Arising from Fire: Fire produces toxic gases including nitrogen oxides, carbon oxides, and ammonia. Vapors may form explosive mixtures with air.
Protective Equipment for Firefighters: Full self-contained breathing apparatus and protective clothing required. Prevent runoff from firefighting from entering drains or water sources.
Fire Hazard Precautions: Remove containers from fire area if safe. Cool fire-exposed containers using water spray. Avoid breathing vapors from fire.
Explosion Data: Vapors heavier than air; may travel to source of ignition and flash back.
Personal Precautions: Evacuate personnel to safe areas. Use appropriate respiratory and skin protection. Keep sources of ignition away from spill area.
Environmental Precautions: Prevent release into sewers, waterways, or soil. Alert local authorities if large spill threatens environment.
Methods for Containment: Contain spillage with non-combustible absorbent material—such as sand, earth, or vermiculite.
Clean-up Procedures: Collect absorbed material in a suitable container for disposal. Ventilate area well after removal of spilled substance.
Disposal: Dispose of materials according to local regulations, ensuring proper handling of contaminated waste streams.
Handling: Use only in well-ventilated areas. Wear proper protective equipment. Avoid all contact with skin, eyes and clothing. Take measures to prevent electrostatic discharge.
Storage Conditions: Store in cool, dry, well-ventilated place, away from incompatible materials like acids and strong oxidizers. Keep container tightly closed. Protect from sunlight, moisture, and heat.
Incompatible Materials: Strong oxidizers, acids, acid chlorides, acid anhydrides.
Special Requirements: Ground and bond containers for static control. Store away from food, drink, and animal feed. Observe all local regulations for flammable liquid storage.
Exposure Limits: Occupational Exposure Limit (OEL): No ACGIH, OSHA, or NIOSH exposure limits established; use good industrial hygiene practice.
Engineering Controls: Use local exhaust ventilation to control airborne vapor concentrations. Maintain eye wash stations and emergency showers.
Personal Protective Equipment (PPE): Respiratory protection required if vapor concentration exceeds recommended limits; organic vapor cartridge or supplied-air respirator. Wear chemical-resistant gloves (nitrile or neoprene), splash-proof goggles or face shield, and flame-retardant clothing.
Hygiene Measures: Wash hands, forearms, and face after handling. Remove contaminated clothing before eating or drinking. Launder clothing regularly.
Appearance: Colorless to pale yellow clear liquid
Odor: Ammonia-like, strong fishy odor
Odor Threshold: 0.06 ppm
pH: Basic (alkaline, typical amine pH in solution 10–11)
Melting Point/Freezing Point: -64°C
Boiling Point: 108–110°C
Flash Point: 17°C (closed cup)
Evaporation Rate: Not available; assumed to evaporate quickly at room temperature
Flammability: Flammable liquid and vapor
Upper/Lower Flammability Limits: 1.5–10% (v/v in air)
Vapor Pressure: 22 mmHg at 20°C
Vapor Density: 4.1 (air = 1)
Relative Density: 0.73–0.75 (water = 1)
Solubility in Water: Miscible
Partition coefficient (n-octanol/water): 1.78
Auto-ignition Temperature: 215°C
Decomposition Temperature: Not established
Viscosity: Not available
Molecular Weight: 129.25 g/mol
Chemical Stability: Stable under normal temperatures and pressures, but heat and direct sunlight accelerate decomposition.
Reactivity: Reacts with acids and strong oxidizers. Produces toxic fumes with thermal decomposition.
Conditions to Avoid: Flames, sparks, extreme heat, pressure build-up in closed containers.
Incompatible Materials: Oxidizing agents, mineral acids, acid chlorides, acid anhydrides.
Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide, ammonia, volatile organic compounds.
Hazardous Polymerization: Will not occur.
Acute Toxicity: Oral LD50 (rat): 1100 mg/kg; Dermal LD50 (rabbit): >2000 mg/kg. Harmful by ingestion or inhalation.
Inhalation Effects: Irritates respiratory tract, coughing, drowsiness, headache possible.
Skin Corrosion/Irritation: Causes irritation, reddening, possible dermatitis on repeated exposure.
Eye Damage/Irritation: Causes severe eye irritation, redness, pain, possible burns.
Chronic Effects: Prolonged or repeated contact may cause skin defatting or dermatitis.
Sensitization: Not classified as skin or respiratory sensitizer.
Carcinogenicity: No evidence found from NTP, IARC, OSHA for carcinogenic potential.
Mutagenicity: No mutagenic effects reported.
Reproductive Toxicity: No evidence at typical exposure levels.
Toxicity to Aquatic Life: Toxic to aquatic organisms, risk of acute and long-term adverse effects in aquatic environment. LC50 (fish): ~100 mg/L (96h, estimated).
Persistence and Degradability: Biodegradable, but persistence possible under certain environmental conditions.
Bioaccumulation Potential: Low, based on partition coefficient.
Mobility in Soil: Mobile, may leach into groundwater if released to environment.
Other Adverse Effects: High concentrations in water can be toxic to algae and fish.
Environmental Precautions: Prevent release to surface waters, conduits, and sewer systems without proper treatment.
Waste Disposal Methods: Dispose of via licensed hazardous waste handler. Incineration preferred under controlled conditions.
Contaminated Packaging: Empty containers must be decontaminated prior to disposal. Do not reuse containers.
Local Regulations: Dispose according to local, regional and national regulations. Avoid discharge into sewage systems and waterways.
Special Precautions: Label all waste and keep segregated from incompatible materials for safe disposal. Follow chemical-specific regulations for hazardous waste.
UN Number: UN1943
UN Proper Shipping Name: Diisobutylamine
Transport Hazard Class: 3 (Flammable liquid)
Packing Group: II
Marine Pollutant: Not listed
Special Precautions: Keep container upright and tightly sealed. Avoid direct sunlight and sources of heat during transit.
Transport Label Requirements: Flammable Liquid (red diamond label)
Regulatory Transport Codes: Refer to DOT, IMDG, IATA for updates and compliance.
Global Regulations: Listed on TSCA (US), EINECS (EU), DSL (Canada), AICS (Australia), and other major inventories.
US SARA Title III: Not a listed Extremely Hazardous Substance; not subject to SARA section 313 reporting.
OSHA Hazard Communication: Classified as hazardous chemical.
EU Classification: Flammable, harmful, irritant. Risk phrases: R10, R20/21/22, R36/38. Safety phrases: S16, S23, S24/25, S36/37/39.
Workplace Controls: Required under EU REACH, US OSHA HAZCOM. Local compliance required for labeling, storage, handling.
Other Regulations: Subject to workplace air monitoring. Risk assessment and documentation required for storage in large volumes.
