Product Name: Dimethylaminopropylamine
CAS Number: 109-55-7
Synonyms: 3-(Dimethylamino)propylamine, N,N-Dimethyl-1,3-propanediamine
Recommended Use: Intermediate in chemical synthesis, surfactant manufacture
Manufacturer Information: Refer to supplier’s contact information on shipping label or purchase documentation, including emergency telephone number for hazards and exposures
Emergency Contact: Chemtrec or local emergency services
GHS Classification: Acute toxicity (oral, dermal, inhalation), skin corrosion/irritation, serious eye damage/irritation, respiratory irritation
Signal Word: Danger
Hazard Statements: Causes severe skin burns and eye damage, toxic if swallowed, harmful if inhaled, causes respiratory tract irritation
Pictograms: Corrosive, exclamation mark
Precautionary Statements: Wear protective gloves, protective clothing, and eye/face protection; Wash thoroughly after handling; Do not breathe dust, fumes, gas, mist, vapors, spray; If in eyes, rinse cautiously with water for several minutes; Remove contact lenses if present and easy to do; Continue rinsing; If swallowed, rinse mouth; Do NOT induce vomiting; Seek immediate medical advice
Chemical Name: Dimethylaminopropylamine
Common Name: DMPA
CAS Number: 109-55-7
Concentration: >99% by weight
Impurities: Minor amounts of related amines possible, not anticipated to contribute additional hazards at normal usage levels
Stabilizing Additives: None typically added
Inhalation: Move person to fresh air; Supply oxygen if breathing is difficult; Seek medical attention immediately for respiratory symptoms
Skin Contact: Remove contaminated clothing; Wash affected skin area thoroughly with soap and water; Seek immediate medical attention in case of burns or irritation
Eye Contact: Immediately flush eyes with water for at least 15 minutes, lifting eyelids occasionally; Remove contact lenses if present; Get medical attention immediately
Ingestion: Rinse mouth thoroughly; Do not induce vomiting unless instructed by medical personnel; Seek medical attention immediately; Never give anything by mouth to an unconscious person
Note to Physician: Treat symptomatically, monitor for respiratory complications and esophageal burns if ingested
Suitable Extinguishing Media: Alcohol-resistant foam, dry chemical, carbon dioxide, water spray (do not use water jet directly on burning product)
Specific Hazards: Vapors may form explosive mixtures with air; May release toxic gases such as nitrogen oxides and carbon dioxide under fire conditions
Protective Equipment for Firefighters: Wear self-contained breathing apparatus (SCBA) and full fire-fighting protective gear
Advice for Firefighters: Cool endangered containers with water spray; Avoid inhaling combustion products; Stay upwind to avoid exposure
Personal Precautions: Use personal protective equipment; Avoid contact with skin, eyes, and clothing; Ensure adequate ventilation
Environmental Precautions: Prevent further leakage or spillage if safe; Do not allow product to enter drains, surface water, or soil
Containment and Clean-Up: Absorb with inert material like sand, earth, or vermiculite; Collect and place in appropriate chemical waste containers for disposal; Thoroughly ventilate affected area
Decontamination: Wash spill site with soap and water after clean-up; Neutralize small residue with dilute acidic solution if necessary
Safe Handling Practices: Use only in well-ventilated areas; Avoid breathing vapors; Avoid contact with skin, eyes and clothing; Keep away from sources of ignition
Storage Conditions: Keep container tightly closed in a dry, cool and well-ventilated location; Store away from oxidizing agents, acids, halogenated compounds
Storage Temperature: Recommend storage at ambient temperature, protected from moisture and incompatible substances
Incompatible Materials: Strong oxidizers, strong acids, copper, zinc, aluminum and their alloys; Avoid contact with acyl chlorides and acid anhydrides due to risk of hazardous reaction
Occupational Exposure Limits: No OSHA PEL or ACGIH TLV specifically established; Maintain exposures as low as achievable
Engineering Controls: Use in closed systems or local exhaust ventilation; Use safety showers and eyewash stations near processing areas
Personal Protective Equipment: Chemical-resistant gloves (nitrile, butyl rubber), protective clothing, chemical splash goggles, face shield; Respiratory protection (NIOSH-approved respirators) if ventilation is inadequate
Hygiene Measures: Wash hands and face after handling; Do not eat, drink or smoke during use; Remove and wash contaminated clothing before reuse
Appearance: Colorless to yellowish transparent liquid
Odor: Amine-like, fishy odor
pH: Strongly alkaline in solution
Melting Point: -60°C
Boiling Point: 134–135°C
Flash Point: 38°C (closed cup)
Evaporation Rate: No data available
Flammability: Flammable liquid and vapor
Vapor Pressure: 5 mmHg at 20°C
Vapor Density: 3.2 (air = 1)
Relative Density: 0.818 g/cm³ at 25°C
Solubility: Miscible with water
Partition Coefficient (n-octanol/water): -0.55 (calculated)
Auto-Ignition Temperature: 280°C
Decomposition Temperature: No data available
Viscosity: 1.39 cP at 20°C
Chemical Stability: Stable under recommended storage conditions
Hazardous Reactions: Reacts violently with strong oxidizing agents, acid chlorides, and acid anhydrides; May form hazardous nitrosamines under certain conditions
Conditions to Avoid: Heat, sparks, open flames, high temperatures, direct sunlight
Incompatible Materials: Strong acids, oxidizers, aldehydes, acid anhydrides, copper, copper alloys, zinc, aluminum
Hazardous Decomposition Products: Ammonia, carbon monoxide, carbon dioxide, nitrogen oxides, dimethylamine, other toxic vapors depending on fire conditions
Routes of Exposure: Inhalation, skin contact, ingestion, eye contact
Acute Toxicity: Oral LD50 (rat): 1870 mg/kg, Dermal LD50 (rabbit): 640 mg/kg, Inhalation LC50 (rat, 4hrs): 6.1 mg/L
Skin Corrosion/Irritation: Strongly corrosive to skin; can cause deep burns
Serious Eye Damage/Irritation: Causes severe eye irritation and possible permanent damage
Respiratory Sensitization: Not classified as a respiratory sensitizer but may cause respiratory tract irritation
Germ Cell Mutagenicity: No evidence from in vitro and in vivo studies
Carcinogenicity: Not listed by IARC, NTP or OSHA as a carcinogen
Reproductive Toxicity: No evidence based on animal or occupational studies
STOT - Single Exposure: May cause respiratory irritation
STOT - Repeated Exposure: No significant adverse effects anticipated at low occupational exposures
Aspiration Hazard: Not classified as an aspiration hazard
Ecotoxicity: Toxic to aquatic organisms, may cause long-lasting effects in the aquatic environment; LC50 (fish, 96 hr): 122 mg/L
Persistence and Degradability: Expected to be biodegradable based on structural properties; biodegradation pathway leads to non-persistent end products
Bioaccumulative Potential: Low (log Pow -0.55)
Mobility in Soil: High; substance migrates easily through soil due to high water solubility
Other Adverse Effects: No data for ozone depletion, global warming potential, or PBT/vPvB assessments
Waste Disposal Methods: Dispose of contents/container in accordance with local, regional, national, and international regulations; Chemical waste should not be disposed via sewage or household waste
Contaminated Packaging: Rinse thoroughly before disposal; Dispose through a licensed hazardous waste facility
Special Precautions: Avoid discharge to the environment or watercourses; Neutralize residue with dilute acid under controlled conditions
Regulatory Guidance: Refer to EPA, local environmental and chemical disposal requirements; Use manifest system where required by law
UN Number: UN 2734
Proper Shipping Name: Amines, liquid, corrosive, flammable, n.o.s. (contains Dimethylaminopropylamine)
Transport Hazard Class: 8 (Corrosive), 3 (Flammable Liquid)
Packing Group: II
Environmental Hazards: Not classified as a marine pollutant
Special Precautions for User: Use sturdy containers to prevent leakage or rupture during transit; Keep away from incompatible shipments; Emergency response guide available from local authorities
Other Transport Requirements: Label containers clearly; Maintain shipping documentation in compliance with DOT, IATA, IMDG, and ADR requirements for hazardous substances
TSCA Status: Listed
EINECS/ELINCS: 203-680-9
REACH Registration: Pre-registered or registered in Europe, subject to inventory notification
Canada DSL: Listed
Australia AICS: Listed
Japan ENCS: 2-324
China IECSC: Listed
South Korea KECI: KE-11219
Hazard Communication: Covered under OSHA Hazard Communication Standard 29 CFR 1910.1200; GHS-compliant
Other Regulations: Reportable under SARA 312 (Fire, Immediate Health Hazard); not RQ listed under SARA 304; State right-to-know laws may impose additional reporting
