Product Name: Homosalate
Chemical Name: 3,3,5-Trimethylcyclohexyl salicylate
CAS Number: 118-56-9
Recommended Uses: Sunscreen agent in personal care formulations
Supplier: Contact manufacturer for details
Emergency Telephone Number: Consult local poison center or emergency service
Classification: Not classified as a hazardous substance according to GHS criteria, though it may cause irritation to eyes or skin upon direct contact.
Label Elements: No mandatory pictograms, precautionary statements suggest avoiding contact with eyes and prolonged skin exposure.
Hazard Statements: May cause mild skin or eye irritation. Not acutely toxic.
Symptoms of Exposure: Redness, itching, or slight burning on skin or eyes upon prolonged exposure.
Precautionary Statements: Wash thoroughly after handling. Avoid breathing dust or vapors.
Chemical Identity: 3,3,5-Trimethylcyclohexyl 2-hydroxybenzoate
Synonyms: Homosalate, HMS
Purity: >95% Homosalate
Impurities: Possible trace organic impurities, quantity depends on manufacturing process
Eye Contact: Rinse cautiously with water for several minutes. Seek medical attention if irritation persists.
Skin Contact: Wash with plenty of soap and water. Remove contaminated clothing.
Inhalation: Move to fresh air. Seek medical advice if symptoms occur.
Ingestion: Do not induce vomiting. Rinse mouth thoroughly. Seek medical attention.
Suitable Extinguishing Media: Use water spray, foam, dry chemical, or carbon dioxide.
Unsuitable Extinguishing Media: Avoid using a direct stream of water, which can spread fire.
Special Hazards: Thermal decomposition may release toxic vapors such as carbon dioxide, carbon monoxide.
Protective Equipment for Firefighters: Wear self-contained breathing apparatus and protective clothing.
Specific Firefighting Methods: Cool containers exposed to fire with water spray to prevent rupture.
Personal Precautions: Put on suitable protective equipment including gloves and eye protection.
Environmental Precautions: Prevent further leakage or spillage if safe to do so. Avoid discharges to soil, waterways, or sewage systems.
Methods for Cleanup: Absorb spillage with inert material such as sand or earth, then transfer to suitable waste containers.
Decontamination: Wash spill area thoroughly with water and detergent after absorption.
Safe Handling: Avoid contact with skin, eyes, and clothing. Use only in well-ventilated areas.
Hygiene Practices: Wash hands thoroughly after handling.
Storage Conditions: Store in tightly closed containers. Keep in a dry, cool, well-ventilated area away from direct sunlight and incompatible substances.
Incompatible Materials: Strong oxidizing agents, acids, and bases should not be stored nearby.
Exposure Limits: No established occupational exposure limits in most regions.
Engineering Controls: Use local exhaust ventilation if dust or vapor is generated.
Personal Protective Equipment: Wear chemical-resistant gloves, protective eyewear, and suitable clothing.
Respiratory Protection: Use a suitable respirator in areas with insufficient ventilation or heavy dust formation.
Environmental Control Measures: Employ spill containment where risk of environmental contamination exists.
Appearance: Clear, colorless to pale yellow liquid
Odor: Mild, characteristic
Odor Threshold: Not available
pH: Not applicable (insoluble in water)
Melting Point/Freezing Point: Approx. -5°C
Boiling Point: Decomposes above 220°C
Flash Point: Approx. 98°C (closed cup)
Evaporation Rate: Not determined
Flammability: May be combustible at elevated temperatures
Vapor Pressure: Low (less than 1 Pa at 20°C)
Solubility: Insoluble in water; soluble in oils and organic solvents
Partition Coefficient (Log Kow): Range 6.2–7
Vapor Density: Not determined
Viscosity: Moderate, oil-like consistency at room temperature
Chemical Stability: Stable under recommended storage conditions.
Reactivity: Not reactive with most substances under normal conditions of storage and use.
Hazardous Reactions: Contact with strong oxidizers can result in hazardous decomposition.
Conditions to Avoid: Heat, sparks, flames, and direct sunlight accelerate decomposition.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, and other unidentified organic compounds in case of fire.
Routes of Exposure: Skin contact, eye contact, ingestion, inhalation (dust or mist)
Acute Toxicity: Low acute oral (LD50 in rats >2000 mg/kg); not considered acutely toxic
Skin Corrosion/Irritation: Mild irritant in sensitive individuals
Eye Damage/Irritation: May cause temporary irritation
Respiratory Sensitization: Not expected based on available data
Chronic Effects: No evidence of carcinogenic, mutagenic, or reproductive effects in animal studies at concentration used in cosmetic products
Other Health Effects: Some reports suggest mild allergic reaction in sensitive individuals
Ecotoxicity: Harmful to aquatic organisms at high concentrations, especially to algae and invertebrates
Persistence and Degradability: Moderately persistent, slow biodegradation in aquatic environments
Bioaccumulative Potential: High octanol-water partition coefficient indicates potential to bioaccumulate
Mobility in Soil: Low, tends to adsorb to soil particles
Other Adverse Effects: Caution advised when discharging rinsates or large volumes directly into water sources
Waste Disposal Methods: Dispose of content/containers according to local, regional, national, and international regulations.
Incineration: Suitable for disposal via incineration in approved facility
Landfill: Place absorbed material in sealed containers before landfill disposal. Do not flush into sewers or natural waterways.
Contaminated Packaging: Containers may be rinsed and recycled or disposed with appropriate labeling as per waste management regulation
UN Number: Not regulated for transport
UN Proper Shipping Name: Not classified as dangerous goods
Transport Hazard Class: Not applicable
Packing Group: Not applicable
Marine Pollutant: Not classified as marine pollutant
Special Precautions: Ensure containers are well sealed and protected during transport to avoid leakage and environmental contamination
Inventory Status: Listed on major chemical inventories including TSCA, REACH, DSL/NDSL, AICS
Cosmetic Regulation: Approved as sunscreen ingredient in various regions within specified concentration limits (typically up to 10% in finished products)
OSHA Hazard Communication: Not classified as a hazardous chemical in the U.S.
Labeling Requirements: Cosmetic products containing homosalate must be labeled as per regional guidelines
Other Regulations: Subject to national and international cosmetic safety regulations and periodic safety reviews concerning environmental and human health impacts
