Product Name: Isopropyl 2-Methylbutanoate
Chemical Family: Ester, organic compound
Molecular Formula: C8H16O2
CAS Number: 97-94-9
Recommended Use: Solvent, flavor, and fragrance ingredient
Supplier Information: Chemical manufacturers and distributors specializing in esters, with support numbers provided for emergencies
Emergency Contact: Reach out by the 24-hour emergency helpline provided on the package or through standard chemical industry emergency numbers such as CHEMTREC
GHS Classification: Flammable liquid (Category 3), Skin irritation (Category 3), Eye irritation (Category 2A)
Signal Word: Warning
Hazard Statements: May cause eye and skin irritation, flammable liquid and vapor
Precautionary Statements: Avoid contact with eyes, skin, or clothing; use only in well-ventilated areas; keep away from ignition sources; ground equipment
Symptoms of Exposure: Irritation of eyes or skin, headache, dizziness, possible central nervous system effects if ingested or inhaled
Pictograms: Flame, exclamation mark
Routes of Entry: Skin contact, inhalation, eye contact, ingestion
Chronic Effects: Long-term exposure rarely reported but repeated or prolonged contact could exacerbate dermal irritation
Chemical Name: Isopropyl 2-Methylbutanoate
Synonyms: Isopropyl ester of 2-methylbutanoic acid
Concentration: ≥99% by weight as supplied
Impurities: Trace amounts of 2-methylbutanoic acid, isopropanol
Additives: No stabilizing additives typically present
Inhalation: Move affected person to fresh air, support breathing as needed, seek immediate medical attention if symptoms persist or worsen
Skin Contact: Remove contaminated clothing immediately, flush affected skin with plenty of running water and soap, consult a healthcare provider if irritation continues
Eye Contact: Rinse with gentle stream of water for at least fifteen minutes, lifting upper and lower eyelids occasionally, obtain medical advice urgently
Ingestion: Rinse mouth thoroughly with water, do not induce vomiting, get medical help promptly, provide medical staff with MSDS
Most Important Symptoms: Burning, redness, stinging sensation; high exposures may cause headaches, confusion, or loss of coordination
Extinguishing Media: Use foam, dry chemical, or carbon dioxide extinguishers for small fires; water spray or fog recommended for larger fires to cool containers
Specific Hazards: Vapors may travel considerable distance to source of ignition and flash back; decomposition may generate carbon monoxide and carbon dioxide
Recommended Protective Equipment: Full firefighting gear including self-contained breathing apparatus; chemical-resistant clothing
Firefighting Procedures: Isolate area, remove all ignition sources, approach fire from upwind, stay clear of low-lying vapors
Combustion Products: Irritating fumes, carbon oxides
Special Concerns: Containers may explode under intense heat; dike runoff to prevent entry into water sources
Personal Precautions: Evacuate unnecessary persons, eliminate all ignition sources, ventilate enclosed areas
Protective Equipment: Gloves, goggles, chemical splash suit, respirator where mist or vapor present
Containment Methods: Prevent leakage from entering water drains, collect with non-sparking tools, dike if possible
Spill Cleanup: Use inert absorbent material such as sand or vermiculite, scoop into suitable container for disposal
Decontamination: Wash affected surface with soap and water; ventilate area adequately before resuming work
Handling Precautions: Handle only in well-ventilated location, ground/bond containers and receiving equipment, avoid creating vapor clouds, do not ingest or inhale
Hygiene Measures: Wash hands thoroughly after handling, remove contaminated clothing before eating or drinking
Storage Recommendations: Store in tightly sealed containers, away from direct sunlight or heat, at ambient temperature in cool, dry, well-ventilated area
Incompatible Materials: Strong oxidizing agents, acids, bases
Storage Class: Flammable liquids storage area, equipped with spill containment
Special Storage Requirements: Use proper labels on containers, monitor for vapor buildup in storage rooms
Occupational Exposure Limits: No specific occupational exposure limits have been established
Engineering Controls: Use explosion-proof ventilation, ensure air exchange rate is sufficient to avoid hazardous vapor concentrations
Personal Protective Equipment: Safety goggles, chemical-resistant gloves (such as nitrile or neoprene), lab coat or chemical apron
Respiratory Protection: NIOSH-approved respirators for handling large quantities, especially where mist or vapor may be present
Environmental Precautions: Prevent release into sewers, waterways, or soil by using spill containment and good ventilation
Appearance: Colorless to pale yellow liquid
Odor: Fruity, sweet, estery
Odor Threshold: Characteristic detection in low ppm range
pH: Neutral in solution
Melting/Freezing Point: -50°C approx
Boiling Point: 165–170°C
Flash Point: 50–56°C (closed cup)
Evaporation Rate: Moderate compared to water
Flammability: Flammable liquid, forms explosive mixtures with air
Vapor Pressure: 1–5 mmHg at 20°C
Vapor Density: Heavier than air
Relative Density (Water = 1): 0.86–0.88
Solubility in Water: Poor; more soluble in organic solvents
Partition Coefficient (n-octanol/water): Estimated high (lipophilic)
Autoignition Temperature: >400°C
Decomposition Temperature: Above 200°C may generate fumes
Viscosity: Thin, low viscosity liquid
Chemical Stability: Stable under standard handling and storage conditions
Reactivity: Responds exothermically to strong oxidizers; contact with open flame or heat leads to rapid vapor formation
Incompatible Materials: Acids, strong bases, oxidizing agents
Hazardous Polymerization: Does not undergo polymerization under normal conditions
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, low-molecular-weight organic compounds possible during thermal breakdown
Conditions to Avoid: Heat, sparks, open flames, static electricity discharges
Routes of Exposure: Inhalation, skin contact, ingestion, eye contact
Acute Toxicity: Exact LD50 (oral, rat) data unavailable, but similar to other isopropyl esters, moderate toxicity
Skin Corrosion/Irritation: Potential for dryness, redness, limited evidence for skin absorption
Serious Eye Damage/Irritation: Possible irritation, tearing, stinging on direct contact
Respiratory Sensitization: Inhalation of vapors may lead to irritation, headache, drowsiness
Germ Cell Mutagenicity: Not classified as mutagenic
Carcinogenicity: No carcinogenic components found in available databases
Reproductive Toxicity: No data indicating reproductive harm
Specific Target Organ Toxicity (STOT): High doses may depress nervous system
Chronic Effects: Long-term effects not well documented; avoid repeated exposure where possible
Medical Conditions Aggravated by Exposure: Dermatitis, asthma, or other respiratory conditions
Ecotoxicity: Toxicity to aquatic organisms remains limited; high concentrations may lead to short-term effects for invertebrates and fish
Persistence and Degradability: Expected to biodegrade through standard environmental processes; hydrolysis and photolysis play a role
Bioaccumulation Potential: Potentially bioaccumulative based on chemical structure and partition coefficient
Mobility in Soil: Mobile in soil, especially if released in liquid form
Other Adverse Effects: Not expected to cause ozone depletion; avoid large releases into industrial waters or sanitary systems; improper disposal could impact aquatic ecosystems due to oxygen demand or direct toxicity
Disposal Methods: Gather residues in clearly labeled containers for hazardous waste processing; incinerate in permitted facility
Contaminated Packaging: Rinse thoroughly, allow to air dry, dispose with hazardous waste collection
Precautions for Disposal: Observe all local, state, and national environmental regulations; incineration strongly preferred for large lots; do not pour down the drain or allow into soil; provide waste handlers with MSDS copy
UN Number: UN 3272
UN Proper Shipping Name: Esters, n.o.s. (contains Isopropyl 2-methylbutanoate)
Transport Hazard Class: 3 (Flammable Liquid)
Packing Group: III (low danger)
Label Requirements: Flammable liquid symbol required
Transport by Land (ADR/RID): Subject to standard flammable liquid regulation
Transport by Sea (IMDG): Category 3; keep away from heat and direct sunlight, stow in cool, ventilated section
Transport by Air (ICAO/IATA): Flammable liquid, transport in approved containers only, follow carrier-specific restrictions
Special Precautions: Prevent spillage, keep containers tightly sealed throughout transit, segregate from foodstuffs and oxidizers, ensure emergency numbers reachable
Safety, Health, and Environmental Regulations: Covered by international, national, and regional chemical safety codes and hazardous materials controls
TSCA Status: Listed in the United States Toxic Substances Control Act Inventory
SARA Title III (Sections 302/304/311/312/313): No components subject to reporting at specified thresholds
EU Regulation (REACH): Pre-registered under REACH; check supplier for registration and supply volume limits
WHMIS Classification (Canada): Controlled, Class B2 (flammable liquids), Class D2B (toxic materials)
Australian AICS Listing: Listed as approved chemical
Label Elements: Appropriate GHS hazard pictograms, hazard and precautionary statements must appear on container
Other Regulatory Details: Provide training for workers; promote risk assessment and workplace safety culture, maintain all workplace documentation and registration up to date
