Product name: Mefrosol
Chemical formula: C17H21NO3
Synonyms: 4-Methoxyphenylpropanolamine
Recommended use: Laboratory reagent, industrial chemical processes
Manufacturer details: Mefrosol Laboratories Ltd., 285 Research Avenue, Cambridge, UK, CB3 0WK, Phone: +44-1223-760000, Email: safety@mefrosol.com
Emergency phone: +44-1223-760001
Product code: MFSL-2023
Hazard class: Acute toxicity (oral and dermal), Skin irritation, Eye irritation
GHS label elements: Signal word: Warning
Pictograms: Exclamation mark
Hazard statements: May cause skin and eye irritation, harmful if swallowed, toxic in contact with skin
Precautionary statements: Avoid dust formation, avoid breathing vapors, wash hands thoroughly after handling, use only outdoors or in well-ventilated area, wear protective gloves and eye/face protection
Potential health effects: May cause respiratory irritation, dizziness, nausea, allergic skin reactions in sensitive individuals
Chemical identity: Mefrosol
CAS number: 123456-78-9
EC number: 412-345-9
Concentration: 98–100% (w/w)
Other components: No significant impurities or additives reported above 1%
Inhalation: Move person to fresh air, keep at rest, seek medical attention if symptoms appear
Skin contact: Remove contaminated clothing, rinse skin with water for at least fifteen minutes, call physician if irritation persists
Eye contact: Rinse cautiously with water for several minutes, remove contact lenses if present, continue rinsing, get medical help
Ingestion: Rinse mouth, do not induce vomiting, call poison center or doctor for advice, never give anything by mouth to an unconscious person
Most important symptoms: May cause nausea, headache, burning sensation, redness, tearing
Suitable extinguishing media: Water spray, dry chemical, foam, carbon dioxide
Unsuitable media: High-volume water jet
Specific hazards: May emit toxic fumes such as carbon monoxide, carbon dioxide, nitrogen oxides under combustion
Special protective equipment: Use self-contained breathing apparatus, protective clothing resistant to chemical exposure
Advice for firefighters: Use water spray to cool containers, avoid inhaling combustion gases, stay upwind
Personal precautions: Evacuate unnecessary personnel, ventilate area, avoid contact with skin and eyes, use personal protective equipment
Environmental precautions: Prevent release into drains, waterways, soil
Methods for containment/cleanup: Absorb with inert material (sand, earth), collect into suitable labeled containers for disposal, wash area with water, prevent dust formation, dispose materials following regulatory guidelines
Handling: Use in well-ventilated area, avoid breathing dust or vapor, avoid contact with skin, eyes, clothing, use proper personal protective equipment
Storage: Store in tightly closed original container, in a cool, dry, well-ventilated place, away from incompatible substances, keep separated from food and feed
Incompatible materials: Strong oxidizing agents, strong acids, alkali metals
Engineering controls: Use exhaust ventilation, safety showers, eyewash stations, local extraction systems for dusts
Personal protective equipment: Safety goggles, chemical-resistant gloves, laboratory coat, suitable respiratory protection
Hygiene measures: Wash hands and face thoroughly after handling, do not eat, drink, or smoke in work area
Occupational exposure limits: Not established for Mefrosol; keep airborne levels as low as possible
Appearance: White to off-white crystalline powder
Odor: Slight, faint amine odor
Melting point: 72–74°C
Boiling point: 332°C
Solubility: Soluble in water, ethanol, ether
Vapor pressure: 0.01 mmHg at 25°C
Relative density: 1.18 g/cm³
pH (100g/L): 7.8
Partition coefficient (n-octanol/water): Log Kow: 1.9
Flash point: 165°C (closed cup)
Chemical stability: Stable under recommended storage conditions
Conditions to avoid: Elevated temperature, moisture exposure, incompatible materials
Incompatible substances: Strong oxidizers, acids
Hazardous decomposition products: Carbon monoxide, carbon dioxide, nitrogen oxides
Polymerization: No hazardous polymerization anticipated under normal conditions
Acute toxicity: LD50 (oral, rat): 410 mg/kg, LD50 (dermal, rabbit): 920 mg/kg
Skin contact: May cause irritation, redness, possible dermatitis on prolonged/excessive exposure
Eye contact: May cause irritation, watering, redness
Inhalation: Coughing, headache, dizziness at high concentrations
Ingestion: Gastrointestinal discomfort, nausea, vomiting
Sensitization: Possible skin sensitizer with repeated/prolonged exposure
Carcinogenicity: No components classified as carcinogen by IARC, NTP, OSHA
Mutagenicity: No data available
Ecotoxicity: Toxic to aquatic life with long lasting effects; LC50 (fish, 96h): 8 mg/L, EC50 (daphnia, 48h): 6 mg/L
Persistence/degradability: Moderately biodegradable in standard OECD tests
Bioaccumulation potential: Low bioaccumulation, Log Kow suggests limited retention in tissues
Mobility in soil: Potential for mobility, soluble in groundwater, may pose risk if released
Other adverse effects: Avoid direct release to water bodies, risk of chemical harm to microorganisms
Waste methods: Dispose through licensed chemical waste contractor, incineration advisable for solids and liquids
Container disposal: Decontaminate, puncture, dispose in accordance with local, regional, national regulations
Precautions: Do not empty into drains or waterways, do not landfill untreated material
UN number: 2811
Proper shipping name: Toxic solid, organic, n.o.s. (Mefrosol)
Transport hazard class: 6.1 (Toxic substances)
Packing group: III
Environmental hazard: Marine pollutant
Transportation modes: Road, rail, air, sea
Special precautions: Avoid contact with containers, use protective equipment when handling during transit
EU regulations: Classified according to Regulation (EC) No 1272/2008 (CLP), safety data sheet available on request, REACH restrictions may apply
US regulations: Subject to Toxic Substances Control Act (TSCA), hazardous chemical under OSHA Hazard Communication Standard
Other international laws: Compliant with UN Recommendations on the Transport of Dangerous Goods, listed in Canada DSL/NDSL
Labeling requirements: GHS-compliant, hazard pictograms, precautionary and hazard statements clearly displayed on packaging
