Chemical Name: Pentylamine
Synonyms: 1-Aminopentane, n-Pentylamine, Amylamine
Chemical Formula: C5H13N
Molecular Weight: 87.16 g/mol
CAS Number: 110-58-7
Recommended Use: Laboratory reagent, intermediate in chemical synthesis, pharmaceutical manufacture
Supplier Identification: Company contact info, emergency phone number always available on site
GHS Classification: Flammable liquid (Category 3), Acute toxicity oral (Category 4), Skin irritation (Category 2), Eye irritation (Category 2A), Acute toxicity inhalation (Category 4)
Signal Word: Warning
Hazard Statements: Flammable liquid and vapor. Harmful if swallowed or inhaled. Causes skin and eye irritation.
Pictograms: Flame, Exclamation mark
Precautionary Statements: Avoid breathing vapors. Wash hands thoroughly after handling. Keep container tightly closed. Ground all equipment containing material. Use explosion-proof equipment. Wear protective gloves, eye protection, and clothing.
Pentylamine: 98–100%
Chemical Formula: C5H13N
Impurities: Less than 1%; typically include residual solvents and water
Other Additives: None
Inhalation: Move person to fresh air. If breathing becomes difficult, provide oxygen or seek medical help.
Skin Contact: Remove contaminated clothing. Rinse skin thoroughly with soap and plenty of water for at least 15 minutes. Seek medical advice.
Eye Contact: Rinse cautiously with water for several minutes. Remove contact lenses if possible without causing harm. Continue rinsing, and get medical attention.
Ingestion: Rinse mouth. Never give anything by mouth to an unconscious person. Get immediate medical attention. Do not induce vomiting unless directed by medical professional.
Symptoms: May include irritation to respiratory tract, coughing, shortness of breath, nausea, vomiting, headache, dizziness, redness, pain in eyes or skin.
Suitable Extinguishing Agents: Foam, dry chemical powder, CO2. Water spray for small fires only; water jet may spread fire.
Special Hazards: Emits toxic fumes of nitrogen oxides, carbon monoxide during combustion. Vapors may form explosive mixtures with air. Containers may rupture under fire condition.
Firefighter Instructions: Firefighters should wear self-contained breathing apparatus and full protective gear. Move containers from fire area if safe. Use caution since reaction with oxidizing agents can explode.
Precaution: Cool closed containers with water spray. Eliminate all ignition sources. Ensure adequate ventilation.
Personal Precautions: Evacuate area. Remove all sources of ignition. Use protective gloves, goggles, and chemical-resistant clothing.
Spill Response: Absorb with sand or inert absorbent. Collect spill using non-sparking tools and place in suitable, labeled containers.
Environmental Precautions: Do not flush into drains, surface water, or soil. Keep out of waterways.
Cleanup Methods: Ventilate area. Dispose of waste as per local regulations. Wash spill site after material pickup is complete.
Handling: Handle in a well-ventilated area away from heat, sparks, and open flame. Avoid all contact with eyes, skin, and clothing. Use risk management measures to keep vapor concentrations as low as possible. Use only spark-proof tools and explosion-proof equipment. Use protective gloves, clothing, goggles, and respiratory protection if risk of overexposure.
Storage: Store in tightly closed original containers in a cool, dry, well-ventilated place away from incompatibles such as strong oxidizers, acids, and sources of ignition. Ground containers and all associated equipment. Protect from sunlight. Prevent contamination and keep away from food or drink.
Occupational Exposure Limits: No established ACGIH or OSHA limits, handle under strict engineering controls.
Engineering Controls: Use in chemical fume hood or equivalent local exhaust ventilation.
Personal Protective Equipment: Safety goggles or face shield, chemical-resistant gloves (nitrile or neoprene), impervious lab coat, respiratory protection (N95 or organic vapor respirator) in case of inadequate ventilation.
Environmental Controls: Prevent release into environment and sewage systems. Implement containment methods for vapor control.
Appearance: Clear, colorless to pale yellow liquid
Odor: Strong, fishy, amine odor
Odor Threshold: Detectable at low concentrations
Boiling Point: 104-106°C (219-223°F)
Melting Point: –60°C (–76°F)
Flash Point: 27°C (81°F), closed cup
Vapor Pressure: 28 mmHg (20°C)
Vapor Density: 3 (Air = 1)
Specific Gravity: 0.76 (water = 1)
Solubility: Miscible with water, alcohol, ether
Partition Coefficient: log Kow = 1.02
Auto-ignition Temperature: 280°C (536°F)
Flammability: Flammable liquid and vapor
Evaporation Rate: Higher than water
pH: Alkaline in solution
Stability: Stable under recommended storage conditions.
Possibility of Hazardous Reactions: Vapors may form explosive mixtures with air. Reacts violently with strong oxidizers, acids, acid chlorides.
Incompatible Materials: Oxidizing agents, strong acids, acid chlorides, copper, zinc, aluminum.
Conditions to Avoid: Flames, sparks, excessive heat, static discharge, open containers.
Decomposition Products: Toxic nitrogen oxides and carbon monoxide produced during thermal decomposition.
Acute Toxicity: Oral LD50 (rat): 180 mg/kg; Inhalation LC50 (rat): 6.4 mg/L/4h
Skin Irritation: Causes irritation, possible burns, redness
Eye Irritation: Causes severe irritation and possible damage
Chronic Effects: Prolonged or repeated exposure may result in dermatitis, respiratory tract irritation, liver or kidney effects
Carcinogenicity: Not classified as a carcinogen by IARC, NTP, ACGIH, or OSHA
Mutagenicity: No available data indicating mutagenicity
Sensitization: May cause allergic skin reactions in some individuals
Additional Information: Harmful if swallowed, inhaled, or absorbed through skin
Ecotoxicity: Toxic to aquatic organisms. LC50 (fish, 96 h): ~100 mg/L
Persistence and Degradability: Expected to be readily biodegradable in the environment
Bioaccumulative Potential: Low (log Kow 1.02)
Mobility in Soil: High mobility due to water solubility
Other Adverse Effects: Risk of contaminating water bodies; hazardous to aquatic life. Prevent spillage or entry into water systems. Avoid release to environment.
Disposal Methods: Collect and deliver waste to approved hazardous waste treatment facility. Comply with local, state, and federal waste disposal regulations.
Incineration: Chemical incinerator with afterburner and scrubber recommended for complete destruction
Container Disposal: Empty containers must be triply rinsed and should not be reused. Dispose according to official requirements.
Avoid: Sewage disposal, landfill, or direct release to environment.
UN Number: UN 2733
UN Proper Shipping Name: Pentylamines
Transport Hazard Class: 3 (Flammable liquid)
Packing Group: II
Labels: Flammable liquid
Environmental Hazard: Not a marine pollutant
Special Precautions: Use appropriate containers. Clearly label and secure load. Emergency procedures must match local transport standards.
OSHA Status: Hazardous chemical under OSHA’s Hazard Communication Standard
TSCA Inventory: Listed
SARA Title III: No specific listing for Section 302/304/313, but general chemical reporting may apply
REACH Registration: Registered in EU if relevant volume handled
Canada WHMIS: Classified B2 (Flammable liquid), D1B (Toxic material)
California Proposition 65: Not specifically listed
Other Regulations: Subject to chemical inventory and reporting regulations. Follow country- and state-level guidance for handling and reporting.
