Product Name: sec-Butylamine
Chemical Formula: C4H11N
Synonyms: 2-Butanamine, Sec-butylamine
CAS Number: 13952-84-6
Recommended Use: Used as a chemical intermediate in pharmaceuticals, rubber chemicals, agricultural products, and corrosion inhibitors
Manufacturer Contact Information: Typically available on the supplier’s label or technical data sheet
Emergency Numbers: Often listed with poison control and manufacturer details
Classification: Flammable liquid, corrosive, acute toxicity (oral, dermal, inhalation)
GHS Label Elements: Signal Word: Danger; Hazard Statements: Highly flammable liquid and vapor, causes severe skin burns and eye damage, toxic if swallowed, toxic if inhaled
Pictograms: Flame, corrosion, skull and crossbones
Potential Health Effects: Causes burns to skin, eyes, respiratory tract; may be fatal if swallowed or absorbed through skin; inhalation can cause headaches, nausea, central nervous system depression
Environmental Impact: Can be harmful to aquatic life if released in large quantities
Chemical Name: sec-Butylamine
CAS Number: 13952-84-6
Concentration: 98-100%
Impurities: Trace amounts of primary and tertiary butylamines possible depending on production
Additives: None reported in pure forms
General Information: Immediate medical attention required for all routes of exposure
Inhalation: Move person to fresh air, administer oxygen if breathing is difficult, give artificial respiration if not breathing
Skin Contact: Remove contaminated clothing, rinse skin thoroughly with water for at least 15 minutes, do not delay medical consult
Eye Contact: Flush eyes with plenty of water for at least 15 minutes, hold eyelids apart, immediate medical consult essential
Ingestion: Do not induce vomiting, rinse mouth, give water if conscious, never give anything by mouth to an unconscious person, immediate medical consult needed
Important Symptoms and Effects: Burning, irritation, lacrimation, breathing discomfort, possible convulsions, coma if ingested or inhaled in large amounts
Suitable Extinguishing Media: Alcohol-resistant foam, dry chemical powder, carbon dioxide. Water spray only to cool containers
Unsuitable Media: Direct water jets (may spread fire)
Specific Hazards in Fires: Can release nitrogen oxides, carbon monoxide, irritating vapors
Protective Equipment: Self-contained breathing apparatus and full protective suit
Special Procedures: Containers near fire should be cooled with water spray to prevent explosion
Personal Precautions: Evacuate area, ventilate, eliminate ignition sources, wear chemical-resistant gloves, goggles, and proper respiratory protection
Environmental Precautions: Prevent from entering drains, surface water, or soil
Cleanup Methods: Absorb with earth, sand, vermiculite, or inert material. Shovel into suitable chemical waste container for disposal
Decontamination: Wash spill site after material pickup is complete. Large spills require specialized response teams
Handling Precautions: Only trained personnel to handle, use in well-ventilated areas or chemical fume hoods; avoid all contact with skin and eyes, anti-static procedures necessary
Safe Storage Conditions: Store in tightly sealed containers in a cool, dry, well-ventilated place, away from direct sunlight, incompatible substances like strong acids, oxidizers, and chlorinated compounds
Transfer Requirements: Ground all equipment to prevent buildup of static electricity
Special Handling Requirements: Emergency showers and eyewash stations should stay close to work areas
Occupational Exposure Limits: US OSHA TWA: 5 ppm (skin), ACGIH TLV: 5 ppm (skin)
Engineering Controls: Chemical fume hood or local exhaust ventilation
Personal Protective Equipment: Flame resistant lab coat, impervious gloves (nitrile or neoprene), chemical splash goggles, face shield in high-exposure scenarios, appropriate organic vapor respirator if ventilation inadequate
Hygiene Measures: Do not eat, drink, or smoke during use; always wash hands after handling
Appearance: Colorless to pale yellow liquid with a strong amine odor
Boiling Point: 63°C (145°F)
Melting Point: -70°C (-94°F)
Flash Point: -18°C (-0.4°F) (closed cup)
Flammability: Highly flammable
Vapor Pressure: 300 mmHg at 20°C
Solubility: Miscible with water, solvents like ethanol and ether
Density: 0.73 g/cm³ at 20°C
Partition Coefficient (Log Pow): 0.62
Auto-ignition Temperature: 272°C (522°F)
Explosive Limits: 1.7%-10.1% (v/v) in air
pH: Basic, not determined for neat liquid
Chemical Stability: Stable at standard temperature and pressure under recommended handling and storage
Conditions to Avoid: Heat, sparks, open flames, static discharge, contact with air or oxidizers
Incompatible Materials: Strong acids, strong oxidizers, acid chlorides, copper alloys
Hazardous Decomposition Products: Ammonia, nitrogen oxides, carbon monoxide, irritating or toxic fumes
Polymerization: Not known to undergo hazardous polymerization
Acute Toxicity: Oral LD50 (rat): 205 mg/kg; Dermal LD50 (rabbit): 200 mg/kg—high toxicity
Inhalation:** Causes irritation of mucous membranes, risk of pulmonary edema in high doses
Skin Corrosion/Irritation: Severe burns, redness, pain, possible necrosis
Serious Eye Damage/Irritation: Causes serious eye damage and burns
Respiratory Sensitization: Breathing vapors may trigger asthmatic responses in sensitive individuals
Repeated Dose Toxicity: Prolonged exposure linked to dermatitis, respiratory issues, CNS effects
Carcinogenicity, Mutagenicity, Reproductive Toxicity: Not listed as a carcinogen by IARC, NTP, or OSHA
Symptoms of Overexposure: Burning sensation, cough, headache, dizziness, nausea, vomiting
Aquatic Toxicity: LC50 (fish, 96 hrs): 118 mg/L; EC50 (daphnia, 48 hrs): 158 mg/L—harmful at high concentrations
Persistence and Degradability: Readily biodegradable in soil and water
Bioaccumulation Potential: Low, due to moderate partition coefficient
Mobility in Soil: Expected to be highly mobile and leach into groundwater
Other Adverse Effects: Potentially toxic to algae and microorganisms if released in bulk
Waste Disposal Methods: Incinerate in a chemical incinerator equipped with afterburner and scrubber; follow all applicable federal, state, and local regulations
Container Disposal: Rinse thoroughly with water, then dispose as hazardous waste
Special Precautions: Do not discharge to natural waters, municipal sewers, or soil
UN Number: UN 1125
Proper Shipping Name: sec-Butylamine
Transport Hazard Class: 3 (Flammable liquid), 8 (Corrosive)
Packing Group: II
Labels Required: Flammable liquid, corrosive
Special Transport Precautions: Keep containers upright, avoid physical damage and heat. Emergency response guide: Flammable & toxic liquids
US Regulations: SARA 313 listed (section 311/312: fire hazard, acute hazard, immediate health hazard)
OSHA: Hazardous chemical; exposure limits enforced
TSCA: Listed
EU Regulations: REACH registered, hazard pictograms required; Seveso Directive applies
Other Regulations: Subject to workplace right-to-know laws, environmental release reporting, and transportation regulations globally
