Product Name: Tetrabutylphosphonium Bromide
Chemical Formula: C16H36BrP
CAS Number: 3115-68-2
Recommended Use: Used in phase transfer catalysis, ionic liquids, and specialty chemicals synthesis.
Manufacturer/Supplier: Contact local chemical suppliers or manufacturer for sourcing information.
Emergency Contact Number: Local poison control or emergency services.
Other Names: TBPB, phosphonium salt.
GHS Classification: Acute toxicity (oral, dermal, inhalation), Skin irritation, Eye irritation, Specific target organ toxicity.
Hazard Statements: Harmful if swallowed, causes skin irritation, causes serious eye irritation.
Pictograms: Exclamation mark, Health hazard.
Signal Word: Warning
Precautionary Statements: Avoid breathing dust/fume/gas/vapors/spray. Wear protective gloves/protective clothing/eye protection/face protection. Wash hands thoroughly after handling.
Chemical Name: Tetrabutylphosphonium Bromide
CAS Number: 3115-68-2
Concentration: ≥ 98% (typical for laboratory grade)
Impurities: Not expected to be present at hazardous levels; trace residual solvents may occur depending on manufacturing.
Synonyms: TBPB, tetrabutylphosphonium salt.
After Inhalation: Move person to fresh air. Seek medical attention if symptoms persist.
After Skin Contact: Wash skin thoroughly with soap and water. Remove contaminated clothing. Medical advice if irritation or rash occurs.
After Eye Contact: Rinse eyes with plenty of water for several minutes, lifting upper and lower eyelids. Seek medical attention if irritation persists.
After Ingestion: Rinse mouth. Do not induce vomiting unless directed by medical personnel. Seek immediate medical advice.
Symptoms/Effects: Irritation of eyes, skin, throat; possible gastrointestinal discomfort if ingested.
Suitable Extinguishing Media: Foam, dry chemical, carbon dioxide, water spray for large fires.
Special Hazards: Combustion may produce toxic fumes of phosphorus oxides, bromide compounds, carbon monoxide, and carbon dioxide.
Advice for Firefighters: Wear self-contained breathing apparatus and full protective gear.
Explosion Data: No data on sensitivity to mechanical impact; chemical is not classified as explosive.
Hazardous Combustion Products: Smoke, corrosive vapors, phosphorus oxides, bromine hydrides.
Personal Precautions: Use gloves, eye protection, and a dust mask or appropriate respiratory protection.
Environmental Precautions: Prevent entry into waterways, drains, or soil.
Methods for Containment: Collect spill with shovel or vacuum; avoid creating dust.
Clean-up Methods: Place collected material in suitable, labelled container for disposal. Wash spill area with detergent and water.
Other Precautions: Ensure adequate ventilation during clean-up.
Precautions for Safe Handling: Avoid inhaling dust or fumes. Use only in well-ventilated environments. Wear recommended personal protective equipment.
Hygiene Measures: Do not eat, drink, or smoke while handling. Wash hands and face after use.
Storage Conditions: Keep container tightly closed. Store in a cool, dry, and well-ventilated location. Protect from moisture and incompatible substances.
Incompatible Materials: Strong oxidizing agents, strong acids, strong bases.
Specific End Uses: As designated in product literature or by technical personnel.
Occupational Exposure Limits: No established exposure limits; minimize exposure through engineering controls and PPE.
Engineering Controls: Local exhaust ventilation, fume hoods, adequate general ventilation.
Eye/Face Protection: Chemical safety goggles.
Skin Protection: Chemical-resistant gloves (nitrile recommended), laboratory coat.
Respiratory Protection: Dust respirator if dust or aerosols are generated; otherwise not typically required.
Other Protective Equipment: Safety shower and eyewash stations should be accessible.
Environmental Exposure Controls: Take measures to prevent release to the environment.
Appearance: White to off-white crystalline solid or powder.
Odor: Slight, characteristic.
Odor Threshold: Not available.
pH: Not determined (aqueous solutions should be neutral to slightly basic).
Melting Point/Freezing Point: Approximately 98-102°C.
Boiling Point: Decomposes before boiling.
Flash Point: Not available; not expected to present a high flammability hazard.
Evaporation Rate: Not applicable.
Flammability (solid, gas): Not classified as highly flammable.
Upper/Lower Flammability or Explosive Limits: Not determined.
Vapor Pressure: Negligible at room temperature.
Vapor Density: Not available.
Relative Density: 1.13 - 1.17 g/cm³.
Solubility in Water: Moderate (increases at elevated temperatures).
Solubility (other): Soluble in polar organic solvents (ethanol, methanol, DMSO).
Partition Coefficient (n-octanol/water): Not available.
Auto-ignition Temperature: Not available.
Decomposition Temperature: Above 200°C.
Viscosity: Not applicable to solid.
Molecular Weight: 352.34 g/mol.
Chemical Stability: Stable under standard laboratory conditions.
Possibility of Hazardous Reactions: Exothermic reaction possible with strong oxidizers and strong acids.
Conditions to Avoid: Excessive heat, open flames, moisture, direct sunlight.
Incompatible Materials: Strong oxidizing agents, mineral acids, strong bases.
Hazardous Decomposition Products: Phosphorus oxides, bromide fumes, carbon monoxide, carbon dioxide, other toxic gases.
Routes of Exposure: Inhalation, ingestion, skin and eye contact.
Acute Toxicity: Harmful if swallowed; oral LD50 (rat) estimated >200 mg/kg (limited data).
Chronic Effects: No long-term studies available; repeated exposure may cause skin dryness or cracking.
Skin/Eye Irritation: Potential for moderate irritation.
Respiratory Effects: Prolonged inhalation may irritate the respiratory tract.
Carcinogenicity: Not classified as carcinogenic based on available data.
Mutagenicity/Teratogenicity: No significant evidence of genetic or reproductive effects.
Other Health Effects: No known specific systemic toxicity at low occupational exposures.
Ecotoxicity: Toxic to aquatic life with long lasting effects.
Aquatic Toxicity: LC50 and EC50 not fully studied; related quaternary phosphonium compounds show toxicity at low mg/L range for fish and daphnia.
Persistence and Degradability: Does not degrade easily in the environment. Stable chemical structure.
Bioaccumulative Potential: Not expected to bioaccumulate due to molecular size and polarity.
Mobility in Soil: Expected to be moderately mobile if released.
Other Adverse Effects: May disrupt aquatic ecosystems at very low concentrations.
Waste Disposal Methods: Dispose of in accordance with local, regional, and national regulations. Incineration recommended for substantial quantities.
Contaminated Packaging: Empty containers should be triple-rinsed, then disposed or recycled as hazardous waste.
Special Precautions: Do not pour down drains or discard in the environment. Document waste streams fully.
UN Number: Not regulated under most transport regulations.
UN Proper Shipping Name: Tetrabutylphosphonium Bromide (not hazardous for transport under GHS/IMDG/ICAO regulations unless bulk quantities).
Transport Hazard Class: Not assigned.
Packing Group: Not regulated.
Environmental Hazards: Not a marine pollutant as per available data.
Special Precautions for User: Avoid package breakage and spills; secure containers during transit.
Transport in Bulk: Avoid during transport of food or feed.
OSHA Hazard Communication: Classified as hazardous chemical.
TSCA Status: Listed.
DSL/NDSL (Canada): Included in inventory.
EU REACH Registration: Polymer exemption or registered intermediates may apply.
EU Classification: Harmful (Xn), Irritant (Xi).
WHMIS Classification (Canada): D2B - Toxic material causing other toxic effects.
SARA Title III, Section 313: Not listed as a reportable chemical.
Other International Regulations: Comply with requirements in specific jurisdictions; consult regional chemical safety guidelines.
