Chemical Name: Triethyl Phosphine Oxide
Chemical Formula: C6H15OP
CAS Number: 554-55-0
Synonyms: TEPO, Triethylphosphine oxide
Recommended Use: Laboratory chemical, organic synthesis, catalyst support
Supplier: Relevant chemical supplier or laboratory supply company
Contact Information: Check with supplier for emergency assistance and additional contact details
Hazard Classification: Not classified as hazardous under GHS guidelines in most jurisdictions but handle with care
Risk Phrases: May cause mild skin and eye irritation, possible inhalation discomfort
Warning Symbols: None required under GHS but prudent lab protocols suggest using standard caution symbols
Potential Health Effects: Contact with eyes or skin could result in irritation. Inhalation may induce throat or respiratory irritation if powder or vapor is present. Ingestion might disturb gastrointestinal tract.
Emergency Overview: Colorless to pale yellow liquid, distinctive odor. Raise awareness in case of poor ventilation or if working in large quantities.
Name: Triethyl Phosphine Oxide
CAS: 554-55-0
Percentage: Greater than 99% purity in most commercial samples
Impurities: Minor traces of related organophosphine compounds in technical grade material, usually less than 1%
Skin Contact: Wash thoroughly with soap and cool water for fifteen minutes. Remove contaminated clothing immediately.
Eye Contact: Rinse gently with clean water for several minutes, lid open. Seek medical attention if redness or discomfort persists.
Inhalation: Move person to fresh air at once. If labored breathing develops or symptoms linger, ask for medical evaluation.
Ingestion: Rinse mouth with water. Do not force vomiting unless instructed by trained personnel or poison center.
Suitable Extinguishing Media: Use water spray, alcohol-resistant foam, dry chemical powder, or carbon dioxide.
Specific Hazards: Product is not considered highly flammable, but combustion produces toxic phosphorus oxides, carbon oxides, and possible ethyl compounds.
Protective Equipment For Firefighters: Wear full protective gear, positive pressure self-contained breathing apparatus.
Advice: Evacuate area and avoid breathing in vapors, fumes, or dust from decomposition.
Personal Precautions: Don chemical-resistant gloves, protective goggles, and suitable lab coat. Ventilate the affected area.
Environmental Precautions: Prevent spillage from spreading into drains or watercourses. Utilize barriers or absorbent materials on hard surfaces.
Spill Procedures: Absorb with inert material like sand or commercial spill kit. Collect in strong, sealable containers for later disposal.
Safe Handling: Keep containers sealed when not in use. Utilize fume hoods or local ventilation to reduce airborne exposure. Avoid inhalation and prolonged skin contact.
Storage Conditions: Store in cool, dry area, away from incompatible substances such as strong acids, strong oxidizers, and reactive halides. Place away from direct sunlight.
Special Requirements: Clearly label storage vessels and isolate chemicals with similar risk profiles.
Engineering Controls: Good general ventilation required. Local exhaust or fume hood improves safety, especially during weighing, transfer, and heating.
Eye Protection: ANSI safety goggles or glasses with side shields recommended.
Skin Protection: Nitrile or neoprene gloves, full-length lab coat.
Respiratory Protection: In poorly ventilated settings, use NIOSH-approved particulate or organic vapor respirator.
Workplace Hygiene: Avoid eating, drinking, or smoking near workstations. Wash hands after handling, even if gloves are worn.
Appearance: Clear, colorless to pale yellow liquid
Odor: Mild, distinct, phosphine-like
Melting Point: About 41°C
Boiling Point: Approximately 215°C
Flash Point: Around 107°C (closed cup)
Solubility: Miscible with water, soluble in ethanol, ether, and most organic solvents
Vapor Pressure: Very low at room temperature
Specific Gravity: About 0.982 g/cm³
pH: Not applicable
Partition Coefficient (n-octanol/water): Data limited, estimate low to moderate
Viscosity: Moderate for organic liquids
Chemical Stability: Stable under standard laboratory and storage conditions.
Conditions to Avoid: High temperatures, open flames, contact with moisture when impurities present.
Incompatible Materials: Strong acids, oxidizing agents, reactive halogens can lead to hazardous decomposition products.
Decomposition Products: Ethylene, phosphorus oxides, potential hydrocarbon fragments on combustion.
Acute Toxicity: Limited data for oral, dermal, or inhalation exposure. In animal studies, low to moderate toxicity levels.
Skin Corrosion/Irritation: Can produce mild but persistent irritation on repeated or prolonged contact.
Eye Damage/Irritation: Redness, watering, or mild discomfort noted.
Inhalation Effects: Minor respiratory tract irritation after significant exposure.
Chronic Effects: No strong evidence of carcinogenicity, mutagenicity, or reproductive toxicity in available research.
Potential Target Organs: Skin, eyes, and upper respiratory system at highest risk.
Ecotoxicity: Data are limited, but similar compounds can be harmful to aquatic organisms at high concentrations.
Persistence and Degradability: Product breaks down slowly in the environment, susceptible to microbial action over long-term exposure.
Bioaccumulative Potential: Not known to bioaccumulate significantly.
Mobility: High water solubility promotes migration in soil and water unless contained.
Other Adverse Effects: Do not intentionally discharge large quantities to the environment.
Waste Treatment Methods: Dispose of through licensed waste handler or chemical incineration facility.
Container Disposal: Triple-rinse empty containers and destroy per regulatory guidelines or return to supplier.
Precautions: Do not release down drain or place in regular trash. Dispose following regional, national, and local environmental regulations.
UN Number: Not assigned for most regions since not regulated as dangerous under ADR, IMDG, IATA
Proper Shipping Name: Triethyl Phosphine Oxide, chemical, not otherwise specified
Transport Hazard Class: Not classified as hazardous for transport
Packing Group: Not assigned
Transport Precautions: Secure tightly in leak-proof containers, maintain upright positioning, avoid high temperatures or direct sunlight during shipment.
Global Inventory Listings: Listed on TSCA (US), REACH (EU), DSL (Canada), and other major international inventories
Regulatory Status: Not subject to strict use limitations; standards for chemical hygiene and safe handling required
Warning Labels: Standard laboratory labels indicating chemical identity, hazard status, and emergency procedures recommended.
Reporting Requirements: No specific reporting needed unless large releases occur or workplace exposures exceed general thresholds.
