Product Name: Triisobutylamine
Synonyms: TIBA; 2,4,6-Tri(propan-2-yl)amine
CAS Number: 35498-54-1
EC Number: 252-039-9
Recommended Use: Industrial chemical, intermediate in organic synthesis
Manufacturer: Supplier contact information appears on product label and invoice.
Emergency Phone Number: Refer to local supplier or emergency services.
Classification: Flammable liquid (Category 3), Acute toxicity oral/inhalation (Category 4), Skin/eye irritant (Category 2)
Label Elements:
Pictogram: Flame, Exclamation mark
Signal word: Warning
Hazard Statements: Flammable liquid and vapor. Harmful if swallowed, inhaled, or in contact with skin. Causes skin and eye irritation.
Precautionary Statements: Keep away from ignition sources. No smoking. Avoid breathing vapor. Wash thoroughly after handling. Wear protective gloves, clothing, and eye/face protection.
Potential Health Effects: Inhalation may cause respiratory tract irritation, dizziness, or headaches. Skin contact may cause redness, dryness, or chemical burns. Eye contact can lead to irritation, redness, and watering. Ingestion produces nausea, abdominal pain, vomiting.
Chemical Name: Triisobutylamine
CAS Number: 35498-54-1
Concentration: ≥ 98%
Impurities: May contain trace organic solvents (≤ 2%), as specified by manufacturer.
Additional Components: No other hazardous contents present at or above reportable thresholds.
Inhalation: Move the person to fresh air. Seek medical attention if symptoms persist. Administer oxygen if breathing is difficult. Remove contaminated clothing.
Skin Contact: Wash with soap and plenty of water for at least 15 minutes. Seek medical help if irritation continues. Remove contaminated clothing and shoes.
Eye Contact: Flush eyes under running water for at least 15 minutes, lifting the eyelids. Get medical attention immediately.
Ingestion: Do not induce vomiting. Rinse mouth. Seek medical assistance. If the individual is unconscious, do not give anything by mouth.
Note to Physician: Symptoms can include burning sensation, cough, wheezing, shortness of breath, and gastrointestinal discomfort.
Suitable Extinguishing Media: Use foam, dry chemical, or carbon dioxide. Water can be used to cool but is less effective for putting out the fire directly.
Special Hazards: Vapors may form explosive mixtures with air. Hazardous combustion products include nitrogen oxides, carbon monoxide, carbon dioxide, and other toxic fumes.
Precautions: Use water spray to cool unopened containers. Evacuate area, remove sources of ignition. Contain runoff.
Protective Equipment: Firefighters should use self-contained breathing apparatus and wear full protective gear to avoid inhalation or skin contact.
Personal Protection: Eliminate all ignition sources. Use respirators, chemical goggles, gloves, and protective clothing.
Spill Response: Absorb with inert material (sand, earth, diatomite), then transfer to suitable containers for disposal. Ventilate area.
Environmental Precautions: Prevent runoff into waterways, sewer, or drains. Notify authorities in case of a large spill.
Decontamination: Wash area with plenty of water after material pick-up is complete.
Handling: Use in a well-ventilated area. Avoid exposure to heat, open flame, or static discharge. Avoid inhalation, ingestion, and contact with skin and eyes.
Storage: Store tightly closed in original labeled containers, away from heat sources. Keep in a cool, dry, well-ventilated area, away from strong oxidizers and acids.
Compatibility: Keep separate from incompatible chemicals, such as strong oxidants and acids.
Special Notes: Keep containers upright to prevent leakage. Inspect regularly for signs of leaks and damage.
Exposure Limits: No established occupational exposure limits for Triisobutylamine; monitor for general vapor threshold (<50 ppm where possible).
Engineering Controls: Use local exhaust ventilation. Emergency eye-wash and shower accessible nearby.
Personal Protection: Wear chemical-resistant gloves (nitrile, butyl), safety goggles, and impermeable clothing. Respiratory protection required if ventilation is inadequate. Use NIOSH-approved organic vapor respirator.
Hygiene Measures: Wash hands after use, before eating, drinking, or smoking. Remove contaminated clothing promptly.
Appearance: Clear, colorless to pale yellow liquid
Odor: Amine-like, strong fishy smell
Boiling Point: 216°C (420°F)
Melting Point: -88°C (-126°F)
Density: 0.80 g/cm³ at 20°C
Solubility: Slightly soluble in water, highly soluble in organic solvents (alcohol, ether)
Vapor Pressure: 0.18 mmHg at 25°C
Flash Point: 88°C (190°F), closed cup
Auto-Ignition Temperature: 380°C (716°F)
Viscosity: 2.1 cP at 20°C
pH: Not applicable (non-aqueous amine)
Chemical Stability: Stable under recommended storage and handling conditions.
Reactivity: Reacts violently with strong acids, oxidizers, and acyl chlorides.
Hazardous Decomposition: Produces toxic gases such as nitrogen oxides, carbon monoxide, and carbon dioxide.
Polymerization: Will not polymerize under normal conditions.
Conditions to Avoid: Heat, flames, sparks, and incompatible materials.
Routes of Entry: Inhalation, ingestion, skin and eye contact
Acute Effects: Irritation of respiratory tract, mucous membranes, gastrointestinal discomfort, headaches, nausea
Chronic Effects: Prolonged or repeated exposure might lead to dermatitis, sensitization, or chronic respiratory symptoms.
Toxicity Data: Oral LD50 (rat): 1,630 mg/kg; Dermal LD50 (rabbit): >2,000 mg/kg
Carcinogenicity: Not listed as a known carcinogen by NTP, IARC, or OSHA
Additional Information: No known reproductive toxicity, mutagenicity, or teratogenicity provided by current data.
Ecotoxicity: Harmful to aquatic life in high concentrations, causes pH shift and oxygen depletion.
Persistence and Degradability: Not readily biodegradable. Risk of bioaccumulation in aquatic environments.
Mobility: Volatile, may evaporate and disperse in air; substance is mobile in soil and water.
Other Adverse Effects: Avoid release to environment. Does not break down easily in sewage or water treatment plants.
Disposal Methods: Collect and arrange disposal through a licensed hazardous waste disposal contractor. Do not discharge to sewers or surface waters.
Container Disposal: Rinse container with suitable solvent, puncture and dispose of as chemical waste.
Legal Regulations: Follow local, regional, and national regulations for hazardous chemical disposal.
Precautions: Do not incinerate closed containers.
UN Number: 2734
UN Proper Shipping Name: Amines, liquid, corrosive, flammable, n.o.s. (Triisobutylamine)
Transport Hazard Class: 3 (Flammable Liquid), 8 (Corrosive)
Packing Group: II
Labels Required: Flammable liquid, Corrosive
Special Information: Protect from direct sunlight and temperature extremes. Keep containers upright and securely fastened during transportation.
Safety, Health, Environmental Regulations: Subject to reporting under TSCA (US), REACH (EU).
SARA Title III: Not listed as an extremely hazardous substance, but reporting may be required for inventory/drainage.
WHMIS (Canada): Classified as flammable and corrosive material.
EU Classification: Xi (Irritant), F (Highly Flammable), per CLP/GHS guidelines.
Other Requirements: Worker safety training, risk assessments, and exposure controls required by most jurisdictions. Consult applicable local laws.
