Chemical Name: Tris(2-ethylhexyl)amine
Synonyms: Trioctylamine, N,N-Di(2-ethylhexyl)-2-ethylhexan-1-amine
CAS Number: 1116-76-3
Recommended Use: Solvent extraction, surfactant, flotation agent, intermediate in chemical manufacturing
Supplier: Information available on request
Emergency Contact: Numbers provided by local emergency services
GHS Classification: Acute toxicity Category 4 (oral, dermal), Skin irritation Category 2, Eye irritation Category 2A, Specific target organ toxicity - single exposure Category 3
Signal Word: Warning
Hazard Statements: Harmful if swallowed or in contact with skin, causes skin and eye irritation, may cause respiratory irritation
Pictograms: Exclamation mark
Precautionary Statements: Avoid breathing dust, vapor, mist; wash skin thoroughly after handling; wear protective gloves, clothing, and eye/face protection; do not eat, drink, or smoke during use; if on skin, wash with soap and water; if in eyes, rinse cautiously with water
Substance: Tris(2-ethylhexyl)amine
Purity: >98%
Impurities: Minor amounts of related amines, hydrocarbons <2%
Molecular Formula: C24H51N
Molecular Weight: 353.67 g/mol
Component: Tris(2-ethylhexyl)amine 100%
Inhalation: Move affected person to fresh air. Obtain medical attention if symptoms persist such as coughing, dizziness, or shortness of breath.
Skin Contact: Remove contaminated clothing and shoes immediately. Wash exposed skin thoroughly with soap and plenty of water. Seek medical care if irritation or rash develops.
Eye Contact: Rinse eyes cautiously with water for several minutes, removing contact lenses if present and easy to do. Continue rinsing and call a physician if irritation persists.
Ingestion: Rinse mouth. Do not induce vomiting. Seek medical attention if feeling unwell. Never give anything by mouth to an unconscious person.
Advice for First Responders: Wear suitable protective clothing. Remove source of exposure if safe to do so. Take the SDS with individual to medical care.
Suitable Extinguishing Media: Use water spray, dry chemical, foam, or carbon dioxide. Select media suited to surrounding fire.
Specific Hazards: May produce toxic fumes of nitrogen oxides, carbon monoxide, and carbon dioxide under fire conditions. Vapors may form explosive mixtures with air.
Protective Equipment: Firefighters require self-contained breathing apparatus and full protective gear.
Special Procedures: Move containers from fire area if safe. Cool containers exposed to fire with water spray. Prevent runoff into drains or waterways.
Fire/Explosion Hazards: Do not breathe combustion products. Flammable liquid and vapor.
Personal Protection: Wear appropriate gloves, eye protection, and chemical-resistant clothing. Keep unprotected personnel away.
Environmental Precautions: Prevent release to soil, drains or water sources. Notify authorities if large spills enter waterways.
Containment: Stop leak if safe to do so. Dike and contain spilled liquid with inert materials such as sand or earth.
Cleanup Method: Collect with non-combustible absorbent material, place in suitable container for disposal. Wash spill area thoroughly. Ventilate area well.
Decontamination: Clean contaminated objects and floors with plenty of water.
Handling: Keep container tightly closed in a dry, well-ventilated area. Avoid contact with eyes, skin, and clothing. Use proper grounding and bonding when transferring material. Avoid inhalation of vapors.
Storage: Store between 5°C and 30°C away from strong oxidizing agents, acids, and sources of ignition. Keep containers tightly sealed and properly labeled.
Technical Measures: Use explosion-proof equipment. Ground/bond container and receiving equipment. Avoid static discharge.
Hygiene Practices: Wash hands and face before eating or drinking. Remove contaminated clothing before entering eating areas.
Occupational Exposure Limits: No workplace exposure limits established for this substance. Keep concentrations as low as possible.
Engineering Controls: Use local exhaust ventilation or process enclosure to keep airborne concentrations below recommended exposure levels.
Respiratory Protection: Wear suitable NIOSH-approved respiratory equipment if ventilation is inadequate or if vapor/mist forms.
Skin Protection: Use impervious gloves, such as butyl or nitrile rubber. Wear protective clothing to prevent skin contact.
Eye Protection: Chemical safety goggles and face shield as appropriate.
General Safety Measures: Emergency eyewash and safety shower facilities should be accessible in the work area.
Appearance: Colourless to pale yellow liquid
Odor: Slight, characteristic amine odor
pH: Not applicable
Melting Point: -59°C
Boiling Point: 176–178°C (at 15 mmHg)
Flash Point: 168°C (closed cup)
Autoignition Temperature: 327°C
Explosion Limits: Data not available
Vapor Pressure: <0.01 mmHg at 20°C
Density: 0.84–0.87 g/cm³ at 20°C
Solubility in Water: Practically insoluble
Solubility in other solvents: Soluble in most organic solvents (alcohols, ethers, hydrocarbons)
Viscosity: 60 mPa·s (20°C)
Partition Coefficient (log Kow): Approx. 8.5
Chemical Stability: Stable under recommended storage and handling conditions.
Conditions to Avoid: Exposure to heat, open flames, static electricity, and direct sunlight.
Incompatible Materials: Strong oxidizing agents, acids, strong reducing agents.
Hazardous Decomposition Products: Burning can produce hazardous fumes of nitrogen oxides and carbon oxides.
Hazardous Reactions: Does not undergo hazardous polymerization.
Likely Routes of Exposure: Inhalation, skin and eye contact, ingestion
Acute Toxicity: Oral LD50 (rat) 2200–3000 mg/kg; Dermal LD50 >2000 mg/kg (rat), causing mild-to-moderate toxicity
Skin Irritation: Causes moderate to severe irritation with prolonged exposure
Eye Irritation: Causes moderate irritation, redness, and tearing
Respiratory Sensitization: May cause respiratory irritation, with coughing or shortness of breath
Carcinogenicity, Mutagenicity, Reproductive Toxicity: Not classified based on available data; long-term studies lacking
Chronic Effects: Long-term contact may result in dermatitis or sensitization
Ecotoxicity: Harmful to aquatic life based on substance profile. LC50 (fish, 96h): 5–10 mg/L (estimated); EC50 (daphnia, 48h): 7–13 mg/L
Persistence and Degradability: Not readily biodegradable in standard tests. Remains persistent in soil and water.
Bioaccumulative Potential: Significant potential for bioaccumulation (log Kow >5).
Mobility in Soil: Low water solubility and high partition coefficient indicate limited mobility and likely adsorption to soil/sediments.
Other Adverse Effects: Toxic to aquatic invertebrates and may disrupt aquatic ecosystems if released.
Waste Treatment Methods: Dispose of in accordance with local, state, and federal regulations. Use registered chemical waste contractor.
Product Disposal: Excess and non-recyclable material to be incinerated in a permitted facility. Dilute residues or small quantities may be absorbed with inert materials.
Contaminated Packaging: Empty containers may retain product vapors or residues; treat as hazardous. Triple rinse and offer for reconditioning or puncture and dispose of as regulated.
Precautions: Prevent waste release to waterways. Do not discharge to sewers.
UN Number: 2734
Proper Shipping Name: Amines, liquid, corrosive, n.o.s. (Tris(2-ethylhexyl)amine)
Transport Hazard Class: 8 (Corrosive material)
Packing Group: III
Labels: Corrosive
Environmental Hazards: Marine pollutant
Special Precautions: Ensure containers are secure and upright during transport. Follow legal requirements specific to locality and mode of transport.
Bulk Transport: Only permitted in appropriate chemical tankers according to international rules.
US TSCA: Listed
EU REACH: Registered or pre-registered
OSHA: Regulated hazardous substance
Canada DSL/NDSL: Listed on DSL
Sara Title III: Not listed for Section 313
Right to Know: Subject to requirements in certain states (New Jersey, Pennsylvania)
EU Classification: Xi; R38, R41, R52/53
Other Information: All applicable directives, regulations and industrial standards apply. Assess workplace & environmental exposure limits.
